A5101780701- Olfactory and Sensory Function Studies
- Nasal Surgery and Airway Studies
- Cardiac Imaging and Diagnostics
- Energy, Environment, Economic Growth
- Cardiovascular Function and Risk Factors
- Vasculitis and related conditions
- Allergic Rhinitis and Sensitization
- Intracerebral and Subarachnoid Hemorrhage Research
- Cardiovascular Health and Risk Factors
- Cardiovascular Health and Disease Prevention
- Veterinary medicine and infectious diseases
- Thermoregulation and physiological responses
- Gastrointestinal Tumor Research and Treatment
- Atherosclerosis and Cardiovascular Diseases
- Cardiac Structural Anomalies and Repair
- Photovoltaic Systems and Sustainability
- Metabolism and Genetic Disorders
- Dialysis and Renal Disease Management
- Drug-Induced Adverse Reactions
- Energy, Environment, and Transportation Policies
- Neurosurgical Procedures and Complications
- Sinusitis and nasal conditions
- Heart Failure Treatment and Management
- Energy and Environment Impacts
- Anesthesia and Pain Management
First Affiliated Hospital Zhejiang University
2025
Southern Medical University Shenzhen Hospital
2024
Third Affiliated Hospital of Southern Medical University
2024
Zhejiang University
2019-2023
Institute of Geographic Sciences and Natural Resources Research
2023
Chinese Academy of Sciences
2023
First Hospital of China Medical University
2023
China Medical University
2023
University of Chinese Academy of Sciences
2023
Second Affiliated Hospital of Xi'an Jiaotong University
2023
Abstract Numerous studies found intestinal microbiota alterations which are thought to affect the development of various diseases through production gut-derived metabolites. However, specific metabolites and their pathophysiological contribution cardiac hypertrophy or heart failure progression still remain unclear. N,N,N-trimethyl-5-aminovaleric acid (TMAVA), derived from trimethyllysine gut microbiota, was elevated with gradually increased risk mortality transplantation in a prospective...
Mounting evidence has linked microbiome and metabolome to systemic autoimmunity cardiovascular diseases (CVDs). Takayasu arteritis (TAK) is a rare disease that shares features of immune-related inflammatory CVDs, about which there relatively limited information. This study was undertaken characterize gut microbial dysbiosis its crosstalk with phenotypes in TAK.To address the discriminatory signatures, we performed shotgun sequencing fecal metagenome across discovery cohort (n = 97) an...
Overabundance of the extracellular matrix resulting from hyperproliferation keloid fibroblasts (KFs) and dysregulation apoptosis represents main pathophysiology underlying keloids. TWEAK is a weak inducer, it plays critical role in pathological tissue remodeling via its receptor, Fn14. However, TWEAK/Fn14 signaling pathogenesis keloids has not been investigated. In this study, we confirmed overexpression levels Fn14 clinical specimens primary KFs. The (ECM)-related genes were also evaluated...
is a highly successful pathogen that poses substantial threat to human health. However, the dynamic interaction between
Establishing the diagnosis and determining disease activity of Takayasu arteritis (TA) remains challenging. Novel biomarkers might help to solve this problem.In screening phase, by using large-scale protein arrays detecting samples from 90 subjects (TA active, 29; TA inactive 31; controls, 30). In validation enzyme-linked immunosorbent assay (ELISA), potential for diagnosis, classification were measured in independent cohorts, respectively.In 18 cytokines significantly differentially...
Intracerebral hemorrhage is the subtype of stroke with highest mortality rate, especially when it also causes secondary intraventricular hemorrhage. The optimal surgical option for intracerebral remains one most controversial areas neurosurgery. We aim to develop a deep learning model automatic segmentation intraparenchymal and clinical catheter puncture path planning. First, we 3D U-Net embedded multi-scale boundary aware module consistency loss segmenting two types hematoma in computed...
Gastric adenocarcinoma of the fundic gland type (GA-FG) is a newly described variant gastric with lack knowledges regarding its genetic features.
Abstract Rectal neuroendocrine neoplasms (rNENs) are among the most frequent gastrointestinal and pose a serious challenge for clinical management. The size of primary neoplasm is considered to be important predictor disease progression, but genetic alterations that occur during progression rNENs remain unknown. Here, we performed comprehensive whole-exome sequencing study on 54 tumor-normal paired, formalin-fixed paraffin-embedded specimens from patients locally diagnosed with rNENs. Of...
We aimed to study the Meta-analysis Global Group in Chronic Heart Failure (MAGGIC) risk model's prognostic value and relationship with left ventricular remodeling dilated cardiomyopathy.Dilated cardiomyopathy patients were prospectively recruited underwent clinical assessments. MAGGIC score was calculated. Patients followed up for adverse events echocardiography. Primary endpoints all-cause mortality first rehospitalization due heart failure. Secondary endpoint defined as a decline ejection...
Background and aims Coronary small vessel disease (CSVD) is often associated with significant percutaneous coronary intervention (PCI) related complications, complex lesions, PCI, poor long-term prognosis. We designed this retrospective study to clarify the characteristics, risk factors, prognostic analyses of CSVD in Chinese populations