Benedetta Rossi
A5106468274- Long-Term Effects of COVID-19
- Pancreatic function and diabetes
- Diabetes Management and Research
- COVID-19 Clinical Research Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Eosinophilic Disorders and Syndromes
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Virology and Viral Diseases
- Gestational Diabetes Research and Management
- SARS-CoV-2 and COVID-19 Research
- Tuberculosis Research and Epidemiology
- Lysosomal Storage Disorders Research
- Viral Infections and Vectors
- Diabetes and associated disorders
- Mosquito-borne diseases and control
- Pneumonia and Respiratory Infections
- Bone health and treatments
- Genetic Neurodegenerative Diseases
- Alcoholism and Thiamine Deficiency
- Global Maternal and Child Health
- Dermatological and COVID-19 studies
- Neutropenia and Cancer Infections
- Rabbits: Nutrition, Reproduction, Health
- Neurological and metabolic disorders
- Yersinia bacterium, plague, ectoparasites research
University of Brescia
2022-2025
Università di Camerino
2023-2025
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
2024-2025
Policlinico Tor Vergata
2023
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori
2019-2022
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2022
University of Rome Tor Vergata
2020-2022
University of Siena
1998-2012
University of Catania
2008
Pregnant women with type 1 diabetes are a high-risk population who recommended to strive for optimal glucose control, but neonatal outcomes attributed maternal hyperglycaemia remain suboptimal. Our aim was examine the effectiveness of continuous monitoring (CGM) on control and obstetric health outcomes.In this multicentre, open-label, randomised controlled trial, we recruited aged 18-40 years minimum 12 months were receiving intensive insulin therapy. Participants pregnant (≤13 weeks 6 days'...
OBJECTIVE To compare glycemic control, quality of life, and pregnancy outcomes women using insulin pumps multiple daily injection therapy (MDI) during the Continuous Glucose Monitoring in Women With Type 1 Diabetes Pregnancy Trial (CONCEPTT). RESEARCH DESIGN AND METHODS This was a prespecified analysis CONCEPTT involving 248 pregnant from 31 centers. Randomization stratified for pump versus MDI HbA1c. The primary outcome change HbA1c randomization to 34 weeks’ gestation. Key secondary were...
OBJECTIVE To determine if temporal glucose profiles differed between 1) women who were randomized to real-time continuous monitoring (RT-CGM) or self-monitored blood (SMBG), 2) used insulin pumps multiple daily injections (MDIs), and 3) whose infants born large for gestational age (LGA) not, by assessing CGM data obtained from the Continuous Glucose Monitoring in Women With Type 1 Diabetes Pregnancy Trial (CONCEPTT). RESEARCH DESIGN AND METHODS Standard summary metrics functional analysis...
Differentiated papillary thyroid cancer is mostly sporadic, but the recurrence of familial form has been reported. Short or dysfunctional telomeres have associated with benign diseases and breast cancer.The aim our work was to study telomere-telomerase complex in peripheral blood patients (FPTC), including measurement relative telomere length (RTL), telomerase reverse transcriptase (hTERT) gene amplification, hTERT mRNA expression, protein activity, search RNA component mutations.Cumulating...
Pancreatic islet transplantation is a promising cell-based therapy for type 1 diabetes (insulin-dependent mellitus), disease triggered by the immune response against autoantigens of beta-cells. However, recurrence after and diabetogenic growth-stunting side effects immunosuppressants are major challenges to application transplantation. Mesenchymal stem cells (MSCs) have recently been reported modulate in allogeneic transplantation.The ability MSCs, either syngeneic or recipients, prevent...
Abstract The aim of this study was to evaluate the role baseline lymphocyte subset counts in predicting outcome and severity COVID-19 patients. Hospitalized patients confirmed be infected with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) were included classified according in-hospital mortality (survivors/nonsurvivors) maximal oxygen support/ventilation supply required (nonsevere/severe). Demographics, clinical laboratory data, peripheral blood subsets retrospectively...
The CONCEPTT trial compared real-time Continuous Glucose Monitoring (RT-CGM) to capillary glucose monitoring in pregnant women with type 1 diabetes. We analyzed CGM and glycated hemoglobin (HbA1c) measures first (n = 221), second 197), third 172) trimesters, aiming examine target attainment associations pregnancy outcomes. targets were Time-in-range (TIR) > 70%, Time-above-range (TAR) <25%, Time-below-range (TBR) < 4%, HbA1c 6.5% (National Institute for Health Care Excellence [NICE]) 6.0%...
Abstract A particular extra‐nodal lymphoma type arises from B cells of the marginal zone (MZ) mucosa‐associated lymphoid tissue (MALT). The aetiology MZ lymphomas suggests that they are associated with chronic antigenic stimulation by microbial pathogens, among which Helicobacter pylori ‐associated gastric MALT is best studied. Recently, have been described in context conjunctivitis, can be Chlamydia spp. infection. Studies Italy showed presence psittaci 87% ocular adnexal (OAL), and C. has...
Abstract Background Our Hospital in Northern Italy assists 3817 people living with HIV (PLWH) and has faced the impact of COVID-19. Little is known about infection on risk post-COVID-19 conditions (PCCs) onset. We aim to assess incidence PCC PLWH factors associated its occurrence. Methods performed a retrospective, observational study including all > 18 years registered Brescia Health Protection Agency database, assessing SARS-CoV-2 burden, vaccination status, socio-demographic,...
Niemann‐Pick type C disease (NPC) is a disorder characterized by abnormal intracellular accumulation of unesterified cholesterol and glycolipids. Two distinct disease‐causing genes have been isolated, NPC1 NPC2. The protein involved in the sorting recycling glycosphingolipids late endosomal/lysosomal system. It has extensive homology with Patched1 (Ptc1) receptor, transmembrane localized primary cilium, Hedgehog signaling (Shh) pathway. We assessed presence Ptc1 proteins evaluated relative...
<b><i>Introduction:</i></b> Acute eosinophilic pneumonia (AEP) is a rare respiratory condition caused by eosinophil accumulation in the pulmonary tissue that can be related to drug administration. Daptomycin, an antibiotic active against gram-positive bacteria, one of leading causes AEP among drugs. In order raise awareness this syndrome, our work we have described case 82-year-old male with <i>Enterococcus faecalis</i> endocarditis treated daptomycin, who...
Contents In a previous study, we reported the short‐ and long‐term effects of bacterial lipopolysaccharide (LPS)‐induced inflammation on rabbit sperm quality. This study was aimed at exploring spermatogenesis model focussing possible damages occurring to testis ejaculated sperm. Twenty New Zealand White bucks were divided into two groups. One group inoculated intra‐peritoneally with LPS, other group, considered as control, treated under same conditions saline only. Semen samples collected...
The aims of this study were to characterize new SARS-CoV-2 genomes sampled all over Italy and reconstruct the origin evolutionary dynamics in Europe between February June 2020. cluster analysis showed only small clusters including < 80 Italian isolates, while most strains intermixed whole tree. Pure observed mainly after lockdown distancing measures adopted. Lineage B B.1 spread late January early 2020, from China Veneto Lombardy, respectively. B.1.1 (20B) probably evolved within central...
Floods, and cyclones are occurring with increasing frequency intensity worldwide due to global warming. Mozambique is very susceptible these extreme events its geographical location. In the last ten years, four of most severe climatic have been observed in this country, leading widespread destruction infrastructure displacement inhabitants. Cyclones Dineo 2017, Idai Kenneth 2019 recently Freddy 2023 affected total over two million people impacting food water security, causing cholera...
The anti-HBc-positive/HBsAg-negative status is frequent in HIV-infection and correlates with poor survival. Here, by highly-sensitive assays, we evaluate cryptic HBV replication factors correlated its detection 81 HIV-infected patients. Patients were treated for >12 months HBV-active modern combined antiretroviral-therapy (cART) had serum HBV-DNA < 20 IU/mL commercial Real-Time PCR. Serum was quantified droplet digital PCR, HBV-RNA an Abbott research assay, anti-HBc titer (proposed to infer...
The results of tuberculosis (TB) screening and reactivation in a cohort 323 adult patients undergoing haematopoietic stem cell transplantation (HSCT) from 2015 to 2019 at the University Hospital Tor Vergata, Rome, Italy, were reported. A total 260 patients, 59 (18.3%) autologous 264 (81.7%) allogeneic transplants, underwent Interferon Release (IFN)-γ (IGRA) test screening: 228 (87.7%) negative, 11 (4.2%) indeterminate 21 (8.1%) positive. Most IGRA-positive Italian origin (95.2%)...