- Viral gastroenteritis research and epidemiology
- Hepatitis Viruses Studies and Epidemiology
- Salmonella and Campylobacter epidemiology
- Listeria monocytogenes in Food Safety
- Probiotics and Fermented Foods
- Veterinary medicine and infectious diseases
- SARS-CoV-2 detection and testing
- Biopolymer Synthesis and Applications
- Microbial Inactivation Methods
- Bacteriophages and microbial interactions
- Hepatitis B Virus Studies
- Protein Hydrolysis and Bioactive Peptides
- Aquaculture disease management and microbiota
- Animal Disease Management and Epidemiology
- Essential Oils and Antimicrobial Activity
- Gut microbiota and health
- Animal Virus Infections Studies
- Animal Nutrition and Physiology
- Biosensors and Analytical Detection
- Food Safety and Hygiene
- Plant Pathogenic Bacteria Studies
- Clostridium difficile and Clostridium perfringens research
- Digestive system and related health
- Tea Polyphenols and Effects
- Virus-based gene therapy research
Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise G. Caporale
2010-2025
Listeriosis, caused by Listeria monocytogenes , is a severe foodborne infection, particularly hazardous for pregnant women and immunocompromised individuals. In Europe, L. was the fifth most reported zoonotic agent in 2022, with outbreaks frequently linked to ready‐to‐eat (RTE) foods. Addressing food contamination innovative antimicrobial strategies critical enhancing safety reducing public health risks. This study evaluated efficacy of two bacteriophage‐derived endolysins, LP101_021...
Hepatitis E virus (HEV) is a zoonotic pathogen with worldwide distribution, and infects several mammalian species, including pigs wild boars, which are recognized as its natural reservoirs. The causes usually self-limiting liver disease mortality rate generally below 1%, although rates of 15%–25% have been recorded in pregnant woman. Chronic infections can also occur. prevalence HEV has extensively studied boars northern Italy, where intensive pig herds predominantly located. In contrast,...
Campylobacteriosis is the most commonly reported gastrointestinal disease in humans. Campybacter jejuni main cause of infection, and bacterial colonization broiler chickens widespread difficult to prevent, leading high risk occurrence meat. Phage therapy represents an alternative strategy control Campylobacter poultry. The aim this work was assess efficacy two field-isolated bacteriophages against experimental infections with anti-microbial resistant (AMR) strain. A two-step phage...
The emergence of new SARS-CoV-2 variants poses challenges to global surveillance efforts, necessitating swift actions in their detection, evaluation, and management. Among the most recent variants, Omicron BA.2.86 its sub-lineages have gained attention due potential immune evasion properties. This study describes development a digital PCR assay for rapid detection descendant lineages, wastewater samples. By using this assay, we analyzed samples collected Italy from September 2023 January...
In 2012 a US multistate outbreak of listeriosis was linked to ricotta salata imported from Italy, made pasteurized sheep's milk. Sampling activities were conducted in Italy trace the source Listeria monocytogenes contamination. The cheese that caused produced plant Apulia processed semi-finished cheeses supplied by five plants Sardinia. During an 'emergency sampling', 179 (23·6%) out 758 end-products tested positive for L. monocytogenes, with concentrations <10 c.f.u./g 1·1 × 106 c.f.u./g....
This literature review was aimed to collect investigations on the in vivo evidences for bacteria associated fermented dairy foods behave as probiotics with beneficial effects prevention and treatment of various diseases. All main bacterial groups commonly present high numbers milks or cheeses were taken into account, namely starter lactic acid (SLAB) Lactobacillus delbrueckii subsp. bulgaricus lactis, L. helveticus, Lactococcus Strepto-coccus thermophilus, non LAB (NSLAB) Lacticaseibacillus...
Hepatitis E virus (HEV) is an emergent zoonotic pathogen, causing worldwide acute and chronic hepatitis in humans. HEV comprises eight genotypes several subtypes. 3 4 (HEV3 HEV4) are zoonotic. In Italy, the most part of infections (80%) due to autochthonous HEV3 circulation virus, key role played by wild animals generally accepted. Abruzzo Italian region officially considered "hot spot", with subtype HEV3-c being up now only one reported among boars. During year 2018-2019, a group boars were...
Foodborne transmission is considered the main way of spreading zoonotic hepatitis E virus (HEV) infection in Europe. In recent years, human cases subjects without history travel endemic areas have raised, suggesting that domestic HEV increasing. Pork products with or liver, are often indicated as source many foodborne well small outbreaks. Pigs recognized reservoir HEV-3 genotype, most frequently detected EU. absence a harmonized surveillance circulation, data on prevalence heterogeneous but...
Human salmonellosis incidence is increasing in the European Union (EU). Salmonellaenterica subsp. enterica serovar Enteriditis, Typhimurium (including its monophasic variant) and Infantis represent targets control programs due to their frequent association with human cases. This study aimed detect most prevalent serotypes circulating Abruzzo Molise Regions between 2015 2020 framework of Italian National Control Program for Salmonellosis Poultry (PNCS)]. A total 332 flocks were sampled by...
Introduction. In May–June 2018, an outbreak of campylobacteriosis involved students and school staff from kindergartens primary schools in Pescara, southern Italy. Aim. We present details the epidemiological microbiological investigation, findings analytical study, as well implemented control measures. Methodology. To identify possible risk factors associated with observed outbreak, a case study was conducted using questionnaire to collect information on date symptoms onset, type duration...
Listeria monocytogenes is a bacterial pathogen responsible of listeriosis, disease that in humans often related to the contamination ready-to-eat foods. Phages are candidate biodecontaminants pathogenic bacteria thanks their ability lyse prokaryotes while being safe for eukaryotic cells. In this study, ΦIZSAM-1 was isolated from drain-waters an Italian blue cheese plant and showed lytic activity against antimicrobial resistant strains. This phage subjected purification vitro efficacy tests....
Hepatitis E virus (HEV) is a zoonotic pathogen, causing infectious hepatitis in man. Pigs and wild boars are the natural asymptomatic reservoirs, while disease humans could be either or evolve hepatitis. In Europe, an increasing number of human infections from HEV have been reported over last few years. The main route transmission through contaminated food, by direct indirect consumption raw undercooked pork boar meat products. Up to now, prevalence Italian northern regions has extensively...
In Europe, very few studies are available regarding the diversity of
800x600 Normal 0 21 false ES X-NONE MicrosoftInternetExplorer4 In a rabbit production facility, health monitoring for enteropathies was performed in 15 cycles 20 mo. For each cycle, up to hundred 35 d old rabbits weaned the same day were randomly selected, reared fattening unit, but separately from source batch and fed with feed except antimicrobial supplementation. Clinical symptoms enteric lesions of selected group recorded, using two checklists binomial response (yes/no answer list 54...
Yersinia enterocolitica causes foodborne disease in humans and infections are usually acquired from contaminated raw or undercooked pork. Pigs considered the primary reservoir of human pathogenic bio-serotypes. A total 376 tonsil tissue samples collected after evisceration cutting pig carcasses were tested for enterocolitica. Animals came an abattoir located Abruzzo region, Italy. was isolated 35 out (9.31%) samples. 47 strains isolated, prevalent bio-serotype 4÷O:3 (95.74%), followed by...
spp. is the second most common bacteria associated with foodborne gastrointestinal outbreaks in humans, highest contamination levels meat, especially poultry.
Wastewater-based epidemiology (WBE) is a recognized, dynamic approach to monitoring the transmission of pathogens in communities through urban wastewater. This study aimed detect and quantify influenza A B viruses Italian wastewater during 2022–2023 season (October 2022 April 2023). total 298 samples were collected from 67 treatment plants (WTPs) across country. These analyzed for (IAV, IBV) using primers originally developed by Centers Disease Control Prevention (CDC) real-time PCR adapted...
Salmonella spp. and hepatitis E virus (HEV) are significant foodborne zoonotic pathogens that impact the health of livestock, farmers, general public. This study aimed to identify biosecurity measures (BSMs) against these on swine farms in Europe, United States, Canada. Overall, 1,529 articles from three scientific databases were screened manually with artificial intelligence (AI) tool ASReview. We identified 54 BSMs 32 articles, primarily focused control. Amongst extracted BSMs, only five...
This study focused on the characterization of lactic acid bacteria (LAB) in a renowned traditional Italian cheese, Pecorino di Farindola, order to select an autochthonous culture and investigate its potential for improvement safety functional properties. Two hundred six LAB isolated throughout production maturation from nine cheese lots three farms were identified by 16S rRNA gene sequencing tested presence genes encoding virulence factors, vancomycin resistance (for enterococci), biogenic...
Hepatitis E virus (HEV) genotype 3 is a prevalent zoonotic pathogen in European pig farms, posing significant public health risk primarily through the foodborne route. The study aimed to identify effective biosecurity measures for controlling HEV transmission on addressing critical gap current knowledge. Utilizing cross-sectional design, fecal samples from gilts, dry sows, and fatteners were collected 231 farms of all farm types across nine countries. Real-time RT-PCR was employed test these...
This study focused on the characterization of lactic acid bacteria (LAB) in a renowned traditional Italian cheese, Pecorino di Farindola, to select an autochthonous culture and investigate its po-tential for improvement safety functional properties. Two hundred six LAB isolated throughout production maturation from nine cheese lots three farms were identified by 16S rRNA gene sequencing tested presence genes encoding virulence factors, vancomycin resistance (for enterococci), biogenic amines...