A5076888924- COVID-19 Clinical Research Studies
- Clinical Laboratory Practices and Quality Control
- Immune cells in cancer
- Mast cells and histamine
- Hematological disorders and diagnostics
- Immunodeficiency and Autoimmune Disorders
- Erythropoietin and Anemia Treatment
- Blood transfusion and management
- Helicobacter pylori-related gastroenterology studies
- T-cell and B-cell Immunology
- SARS-CoV-2 detection and testing
- Statistical and Computational Modeling
- Inflammation biomarkers and pathways
- COVID-19 and healthcare impacts
- Inhalation and Respiratory Drug Delivery
- Respiratory Support and Mechanisms
- SARS-CoV-2 and COVID-19 Research
- Dermatological and COVID-19 studies
- Gastric Cancer Management and Outcomes
- Blood groups and transfusion
- Cancer-related molecular mechanisms research
Charité - Universitätsmedizin Berlin
2019-2024
Vivantes Klinikum
2019-2024
Freie Universität Berlin
2019-2022
Humboldt-Universität zu Berlin
2019-2022
Medical University of Vienna
2015
Abstract COVID-19 (coronavirus disease 2019) patients often show excessive activation of coagulation, associated with increased risk thrombosis. However, the diagnostic value coagulation at initial clinical evaluation is not clear. We present an in-depth analysis in presenting to emergency department (ED) suspected COVID-19. N = 58 clinically ED were enrolled. 17 subsequently tested positive using SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) polymerase chain reaction (PCR)...
Lactate dehydrogenase (LD) is an enzyme involved in glucose metabolism with critical clinical significance both outpatients and inpatients.1 In hematological cancer patients, high levels of LD are often associated advanced disease, tumor burden, cell death thus play important role the diagnosis, monitoring, prognosis.2, 3 Elevated older patients can indicate a range underlying health problems. However, interpreting adults be challenging due to age-related changes higher prevalence...
Abstract The PI3K signaling cascade in APCs has been recognized as an essential pathway to initiate, maintain, and resolve immune responses. In this study, we demonstrate that a cell type–specific loss of the antagonist phosphatase tensin homolog (PTEN) myeloid cells renders toward regulatory phenotype. deficient for PTEN exhibit reduced activation p38 MAPK expression T cell–polarizing cytokines. Furthermore, deficiency leads upregulation markers alternative activation, such Arginase 1, with...
Abstract Background Lactate dehydrogenase (LD) activity is routinely monitored for therapeutic risk stratification of malignant diseases, but also prone to preanalytical influences. Methods We systematically analyzed the impact defined conditions on hemolysis-susceptible parameters LD, potassium (K) and hemolysis index in vacuum blood collection tubes (serum [SE], heparin plasma [HP]). Blood was collected by venipuncture from healthy volunteers. Tubes were either filled or underfilled...
Abstract Background : A total of 62/66 (93.9%) residents in a senior citizen home Bremen, Germany, received the first dose Biontech/Pfizer vaccine BNT162b2 on December 27th 2020. After routine severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) antigen tests showed positive results January 5th, all and staff were tested by RT‐PCR. Results Nine members 23 had result. PCR reported mild to COVID‐19 symptoms, one was hospitalized. None them been vaccinated. In contrast, vaccinated no or...