Joscha Böhnlein
A5067464637- Functional Brain Connectivity Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Mental Health Research Topics
- Advanced Neuroimaging Techniques and Applications
- Child Abuse and Trauma
- Neural and Behavioral Psychology Studies
- Resilience and Mental Health
- Child and Adolescent Psychosocial and Emotional Development
- Advanced MRI Techniques and Applications
- Memory and Neural Mechanisms
- Stress Responses and Cortisol
- Early Childhood Education and Development
- Psychosomatic Disorders and Their Treatments
- Tryptophan and brain disorders
- Treatment of Major Depression
- Schizophrenia research and treatment
- Electroconvulsive Therapy Studies
- Digital Mental Health Interventions
- Transcranial Magnetic Stimulation Studies
- Child and Adolescent Health
- Maternal Mental Health During Pregnancy and Postpartum
- Human Health and Disease
- EEG and Brain-Computer Interfaces
- Statistical Methods in Clinical Trials
- Traumatic Brain Injury Research
University of Münster
2017-2025
University Medical Center Hamburg-Eppendorf
2024-2025
Universität Hamburg
2024-2025
European Neuroendocrine Tumor Society
2024
Humboldt-Universität zu Berlin
2024
University of Freiburg
2024
Charité - Universitätsmedizin Berlin
2024
Universitätsklinikum Würzburg
2024
Universität Greifswald
2024
University Hospital Münster
2019-2021
Childhood adversity is a strong predictor of developing psychopathological conditions. Multiple theories on the mechanisms underlying this association have been suggested which, however, differ in operationalization ‘exposure.’ Altered (threat) learning represent central by which environmental inputs shape emotional and cognitive processes ultimately behavior. 1402 healthy participants underwent fear conditioning paradigm (acquisition training, generalization), while acquiring skin...
Introduction Specific phobia (SPH) is a prevalent anxiety disorder and may involve advanced biological aging. However, brain age research in psychiatry has primarily examined mood psychotic disorders. This mega-analysis investigated aging SPH participants within the ENIGMA-Anxiety Working Group. Methods 3D structural MRI scans from 17 international samples (600 individuals, of whom 504 formally diagnosed 96 questionnaire-based cases; 1,134 controls; range: 22-75 years) were processed with...
Data-based predictions of individual Cognitive Behavioral Therapy (CBT) treatment response are a fundamental step towards precision medicine. Past studies demonstrated only moderate prediction accuracy (i.e. ability to discriminate between responders and non-responders given treatment) when using clinical routine data such as demographic questionnaire data, while neuroimaging achieved superior accuracy. However, these may be considerably biased due very limited sample sizes bias-prone...
Abstract Background Electroconvulsive therapy (ECT) is a fast-acting intervention for major depressive disorder. Previous studies indicated neurotrophic effects following ECT that might contribute to changes in white matter brain structure. We investigated the influence of non-randomized prospective study focusing on over time. Methods Twenty-nine severely depressed patients receiving addition inpatient treatment, 69 with treatment (NON-ECT) and 52 healthy controls (HC) took part study....
Abstract Objectives Embedded in the Collaborative Research Center “Fear, Anxiety, Anxiety Disorders” (CRC‐TRR58), this bicentric clinical study aims at identifying biobehavioral markers of treatment (non‐)response by applying machine learning methodology with an external cross‐validation protocol. We hypothesize that a priori prediction is possible second, independent sample based on multimodal markers. Methods One‐session virtual reality exposure (VRET) patients spider phobia was conducted...
Background The general understanding of the ‘vulnerability–stress model’ mental disorders neglects modifying impact resilience-increasing factors such as coping ability. Aims Probing a conceptual framework integrating both adverse events and in an extended ‘vulnerability–stress–coping disorders, effects functional neuropeptide S receptor gene ( NPSR1 ) variation (G), early adversity (E) (C) on anxiety were addressed three-dimensional G × E C model. Method In two independent samples healthy...
Abstract Childhood maltreatment is associated with cognitive deficits that in turn have been predictive for therapeutic outcome psychiatric patients. However, previous studies either investigated associations single domains or failed to adequately control confounders such as depression, socioeconomic environment, and genetic predisposition. We aimed isolate the relationship between childhood dysfunction diverse domains, while estimating contribution of potential this relationship,...