A5102020141- Congenital heart defects research
- Congenital Heart Disease Studies
- Tissue Engineering and Regenerative Medicine
- Cancer, Stress, Anesthesia, and Immune Response
- Metabolomics and Mass Spectrometry Studies
- Infective Endocarditis Diagnosis and Management
- RNA modifications and cancer
- Advanced ceramic materials synthesis
- Glioma Diagnosis and Treatment
- Cardiac tumors and thrombi
- Electrospun Nanofibers in Biomedical Applications
- Aluminum Alloys Composites Properties
- Blood Coagulation and Thrombosis Mechanisms
- Coronary Artery Anomalies
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Cardiac Valve Diseases and Treatments
- Viral Infections and Immunology Research
- Pluripotent Stem Cells Research
- Intensive Care Unit Cognitive Disorders
- Diagnosis and treatment of tuberculosis
- Cancer-related molecular mechanisms research
- Intracerebral and Subarachnoid Hemorrhage Research
- Advanced materials and composites
- Traumatic Brain Injury and Neurovascular Disturbances
- Healthcare and Venom Research
Kunming Medical University
2015-2025
Yan'an Hospital Affiliated To Kunming Medical University
2015-2025
First Affiliated Hospital of Hebei Medical University
2017-2025
Hebei Medical University
2017-2024
Qingdao University
2023
Affiliated Hospital of Qingdao University
2023
Wuhan University of Science and Technology
2014-2023
Hunan Normal University
2023
Chang'an University
2022
Qinghai Normal University
2022
This study aims to identify appropriate innovative strategies for solar energy investments both commercial and non-commercial users. For this purpose, TRIZ-based 8 different are identified. Later, these weighted with the interval type-2 fuzzy DEMATEL (IT2 FDEMATEL) method define more important strategies. Thus, main motivation of is figure out weights The findings indicate that replacement mechanical system found as most effective investment strategy projects regarding customers. it...
Studies have shown significantly increased thromboembolic events at high altitude. We recently reported that transferrin could potentiate blood coagulation, but the underlying mechanism for altitude-related thromboembolism is still poorly understood. Here, we examined activity and concentration of plasma coagulation factors in collected from long-term human residents short-stay mice exposed to varying altitudes. found activities thrombin factor XIIa (FXIIa) along with concentrations were...
Abstract Coagulation balance is maintained through fine-tuned interactions among clotting factors, whose physiological concentrations vary substantially. In particular, the of coagulation proteases (pM to nM) are much lower than their natural inactivator antithrombin (AT, ~ 3 μM), suggesting existence other coordinators. current study, we found that transferrin (normal plasma concentration ~40 μM) interacts with fibrinogen, thrombin, factor XIIa (FXIIa), and AT different affinity maintain...
Metastasis associated lung adenocarcinoma transcript 1 (MALAT1) plays an important role in vascular remodeling. Down-regulation of MALAT1 can inhibit the proliferation endothelial cells and smooth muscle cells, reduce cardiomyocyte apoptosis improve left ventricular function, which is closely linked to numerous pathological processes such as coronary atherosclerotic heart disease (CAD). The aim this study was investigate whether polymorphisms were with susceptibility CAD.A total 508 CAD...
Abstract Blood clot formation induced by dysfunctional coagulation is a frequent complication of coronavirus disease 2019 (COVID-19) and high-risk factor for severe illness death. Neutrophil extracellular traps (NETs) are implicated in COVID-19-induced immunothrombosis. Furthermore, human cathelicidin, NET component, can perturb the interaction between SARS-CoV-2 spike protein its ACE2 receptor, which mediates viral entry into cells. At present, however, levels cathelicidin antimicrobial...
Microwave-absorbing materials adapting to high temperatures and harsh environments are in great demand. Herein, a core-shelled Ti3AlC2@La2Zr2O7 (TAC@LZO) composite was designed fabricated by encapsulating the La2Zr2O7 (LZO) thermal insulation ceramic on surface of highly conductive Ti3AlC2 (TAC) via chemical coprecipitation subsequent heat treatment. The continuous LZO coating improved oxidation resistance at 600 °C modulated its dielectric properties. TAC@LZO exhibited an excellent...
Rheumatic mitral stenosis (RMS) is the most common manifestation of rheumatic heart disease, with high morbidity and mortality. Interleukin-35 (IL-35) a novel anti-inflammatory cytokine associated many autoimmune diseases. However, relation between IL-35 expression RMS remains unknown. We aimed to study in its association disease progression. concentration was analyzed blood samples from 40 patients, including 20 moderate, severe RMS, healthy controls by ELISA. Mitral valve (MV) determined...
Gallbladder carcinoma (GBC) is the most common and aggressive cancer of biliary tract. Liensinine has been proved to have hypotensive effect. However, effect liensinine on GBC still unknown. The aim this study investigate mechanism in human cells. Cell viability assay colony formation were performed assess cell growth proliferation. Flow cytometry analysis was used cycle apoptosis vitro. Hoechst 33342 staining also evaluate apoptosis. Western blot determine expression proteins corresponding...
The success of developing cardiovascular tissue engineering (CTE) grafts greatly needs a readily available cell substitute for endothelial and interstitial cells. Perinatal annexes have been proposed as valuable source mesenchymal stem cells (MSCs) regenerative medicine. objective the present study is to evaluate potential human Wharton's jelly MSCs (WJ-MSCs) amniotic membrane (AM-MSCs) seeding in CTE WJ-MSCs/AM-MSCs were isolated characterized vitro according their morphology,...
To investigate whether plasma concentrations of S100β protein, neuron-specific enolase (NSE), and neuroglobin (NGB) correlate with early postoperative cognitive dysfunction (POCD) in patients undergoing total arch replacement.This prospective study analyzed 40 who underwent replacement combined stented elephant trunk implantation at our hospital between March 2017 January 2019. Cognitive function was assessed using the Mini-mental State Examination (MMSE) preoperatively, on day after...
Despite improvements in management, infective endocarditis (IE) is still associated with high mortality and morbidity. The outcome of patients IE remains unclear high-altitude areas China. To characterize the epidemiological features surgical outcomes, a retrospective analysis was conducted to 221 diagnosed from single center. In addition, assess prognosis patients, multivariate logistic regression model performed analyze affecting risk factors.
Inconsistent results were reported in recent literature regarding the association between methylenetetrahydrofolate reductase (MTHFR) C677T/A1298C polymorphisms and susceptibility of congenital heart disease (CHD). In this study, we performed a meta-analysis to investigate associations by employing multiple analytical methods.Literature search was published articles obtained from PubMed, Embase CNKI databases based on exclusion inclusion criteria. Data extracted eligible studies crude odds...
Primary malignant peripheral nerve sheath tumors (MPNSTs) are extremely rare in patients without a history of neurofibromatosis; only 18 cases have been reported the English-language literature to this point. The authors report their experience with 1 new case primary MPNST. A 33-year-old woman presented low-back pain radiating right calf that progressed over year. Magnetic resonance imaging spine revealed an intradural extramedullary lesion at T12-L1 level. patient was diagnosed MPNST,...
Abstract Although detergent‐based decellularization protocols have been widely used to obtain a natural extracellular matrix (ECM) scaffold in tissue engineering, some key challenges still exist. To achieve an optimum decellularized for the construction of tissue‐engineered small‐diameter blood vessels (TEBV), porcine carotid arteries (PCAs) were by combining sodium dodecyl sulfate (SDS), deoxycholate (SDC) and Triton X‐100 (Triton) different concentrations. Tissue samples processed their...
BACKGROUND The NKX2 gene family is made up of core transcription factors that are involved in the morphogenesis vertebrate heart. NKx2-5 plays a pivotal role mouse cardiogenesis, and mutations result an abnormal structure function heart, including atrial septal defect cardiac electrophysiological abnormalities. MATERIAL AND METHODS To investigate genetic variation NKX2-5 Chinese patients with sporadic defect, we sequenced full length participants study. Four hundred thirty-nine 567 healthy...
Abstract A series of high alumina refractory castables were prepared via casting with tabular aggregates (0.088 – 5 mm), fine powders, and calcium aluminate cement as starting materials. The effect the median diameter ( D 50 = 7.26 μm, 5.33 2.37 μm) on thermo-mechanical properties was investigated. results indicate that decrease in particle size from μm to has little influence both apparent porosity bulk density castables. However, pore fired after 1 600 °C decreased drastically 4.7 2.4...