A5047221965- Organ Donation and Transplantation
- Organ Transplantation Techniques and Outcomes
- Xenotransplantation and immune response
- Palliative Care and End-of-Life Issues
- Neuroethics, Human Enhancement, Biomedical Innovations
- Organ and Tissue Transplantation Research
- Grief, Bereavement, and Mental Health
- Long-Term Effects of COVID-19
- Renal Transplantation Outcomes and Treatments
- Liver Disease and Transplantation
- Tissue Engineering and Regenerative Medicine
- Doping in Sports
- Ethics in Clinical Research
- Cardiac Arrest and Resuscitation
- LGBTQ Health, Identity, and Policy
- Transplantation: Methods and Outcomes
- Reproductive Health and Technologies
- Biomedical Ethics and Regulation
- COVID-19 Clinical Research Studies
- CRISPR and Genetic Engineering
- Reconstructive Surgery and Microvascular Techniques
- SARS-CoV-2 and COVID-19 Research
- Anesthesia and Neurotoxicity Research
- Ethics in medical practice
- Pancreatic and Hepatic Oncology Research
New York University
2015-2025
Broad Institute
2024
NYU Langone Health
2012-2024
Dana-Farber Cancer Institute
2024
Hinge Health
2019-2024
International Society for Heart and Lung Transplantation
2023
Miami Transplant Institute
2023
Fundación Juan March
2022
Zero to Three
2018
Institute of Medical Ethics
2018
Xenografts from genetically modified pigs have become one of the most promising solutions to dearth human organs available for transplantation. The challenge in this model has been hyperacute rejection. To avoid this, bred with a knockout alpha-1,3-galactosyltransferase gene and subcapsular autologous thymic tissue.We transplanted kidneys these into two brain-dead recipients whose circulatory respiratory activity was maintained on ventilators duration study. We performed serial biopsies...
On June 3, 2023, the American Society of Transplant Surgeons convened a meeting in San Diego, California to (1) develop consensus statement with supporting data on ethical tenets thoracoabdominal normothermic regional perfusion (NRP) and abdominal NRP; (2) provide guidelines for standards practice that should govern NRP (3) implement central database collection donor recipient United States. National international leaders fields neuroscience, transplantation, critical care, NRP, Organ...
This paper responds to the position statement released by American College of Physicians (ACP) entitled "Ethics, Determination Death, and Organ Transplantation in Normothermic Regional Perfusion (NRP) with Controlled Donation after Circulatory Death (cDCD): Statement Concern." The ACP's engages critical ethical issues surrounding cDCD NRP, but several their conclusions are flawed. Contrary statement, practice respects dead donor rule legal definition death while honoring wishes deceased...
Abstract Genetic testing is becoming more widespread, and its capabilities predictive power are growing. In this paper, we evaluate the ethical justifications for strength of US legal framework that aims to protect patients, research participants, consumers from genetic discrimination in employment health insurance settings context advancing technology. The Information Nondiscrimination Act (GINA) other laws prohibit health-related United States, but these have significant limitations, some...
Controlled heart donation after circulatory determination of death (cDCD) is well established internationally with good outcomes and could be adopted in the United States to increase supply if ethical logistical challenges are comprehensively addressed. The most effective resource-efficient method for mitigating warm ischemia arrest normothermic regional perfusion (NRP) situ. This strategy requires restarting circulation declaration according criteria, which appears challenge legal...
As the USA contends with another surge in COVID-19 cases, hospitals may soon need to answer unresolved question of who lives and dies when ventilator demand exceeds supply. Although most triage policies have seemingly converged on use clinical benefit as primary criteria for prioritisation, significant differences exist between institutions how assign priority patients identical medical prognoses: so-called ‘tie-breaker’ situations. In particular, one’s status a frontline healthcare worker...
This article's main contributions are twofold: 1) to demonstrate how apply the general European Union's High-Level Expert Group's (EU HLEG) guidelines for trustworthy AI in practice domain of healthcare and 2) investigate research question what does "trustworthy AI" mean at time COVID-19 pandemic. To this end, we present results a post-hoc self-assessment evaluate trustworthiness an system predicting multiregional score conveying degree lung compromise patients, developed verified by...
Abstract The standard treatment for end‐stage organ failure is transplantation, but demand organs has always vastly outstripped supply. Discussions are ongoing about the feasibility of addressing shortage through measures like increasing donations, improving post‐transplant outcomes, and xenotransplantation. This paper examines rationale, risks, costs xenotransplantation, such as xenozoonoses, creating a new form industrialized animal farming, abandoning ethics principles, opportunity...
ABSTRACT Religious viewpoints have been shown to influence the ways in which many persons approach medical decision‐making and noted as a potential barrier xenotransplantation acceptance. This study sought explore how attitudes toward differ among various religious beliefs. A national Likert‐scale survey was conducted 2023 with representative sample United States. belief self‐reported. Regression analysis used identify associations hesitations about xenotransplantation. Five thousand eight...
Purpose of review Donation after circulatory death (DCD) is one the most promising methods for expanding organ pool transplantation. Yet realizing promise DCD depends on careful coordination end life treatment with donation authorization, preservation, and recovery. Recent findings As procurement organizations (OPO) increase their efforts, challenges regarding timely referral, delays in recovery coordination, requisite separation clinical decisions from are potentially preventing successful...
Despite the growing success of facial transplantation, organ donor shortages remain challenging. Educational health campaigns can effectively inform general public and institute behavioral modifications. A brief educational introduction to transplantation may positively influence public's position on donation.The authors anonymously surveyed 300 participants, gathering basic demographic information, registration status, awareness willingness donate solid organs allografts. Two-hundred these...