A5100400834- Endometrial and Cervical Cancer Treatments
- Genetic factors in colorectal cancer
- Lymphoma Diagnosis and Treatment
- CAR-T cell therapy research
- Dermatology and Skin Diseases
- Cancer-related molecular mechanisms research
- Management of metastatic bone disease
- Metabolomics and Mass Spectrometry Studies
- Lung Cancer Diagnosis and Treatment
- Intraperitoneal and Appendiceal Malignancies
- BRCA gene mutations in cancer
- Asthma and respiratory diseases
- Radiomics and Machine Learning in Medical Imaging
- Reproductive Biology and Fertility
- Allergic Rhinitis and Sensitization
- Prostate Cancer Treatment and Research
- Neuroendocrine Tumor Research Advances
- Digital Marketing and Social Media
- Urticaria and Related Conditions
- Cancer Genomics and Diagnostics
- Sarcoma Diagnosis and Treatment
- Pregnancy and preeclampsia studies
- Monoclonal and Polyclonal Antibodies Research
- Technology Adoption and User Behaviour
- Lung Cancer Treatments and Mutations
Peking University
2015-2025
Peking University People's Hospital
2015-2025
Peking University Cancer Hospital
2017-2024
Affiliated Hospital of Qingdao University
2022-2024
University of Alabama at Birmingham
2024
Shanxi Medical University
2014-2023
AmerisourceBergen (United States)
2023
Qingdao University
2022-2023
First Hospital of Shanxi Medical University
2014-2023
USC Norris Comprehensive Cancer Center
2021-2022
Recently, two patients with primary ovarian insufficiency (POI) delivered healthy babies after in vitro activation (IVA) treatment followed by auto-transplantation of frozen-thawed tissues.This study sought to report the first case live birth IVA following fresh tissue grafting POI, together monitoring follicle development and serum hormonal changes.This was a prospective observational cohort study.We performed 14 POI mean age 29 years, duration since last menses 3.8 average basal FSH level...
Abstract We compared combination treatment with teriparatide plus raloxifene alone in women postmenopausal osteoporosis a 6-month double-blind, placebo-controlled trial that measured biochemical markers of bone turnover and BMD. Markers formation spine BMD increased similarly therapy. However, therapy induced significantly smaller increase resorption versus total hip baseline. Introduction: The effects combining two approved treatments for different modes action were examined by comparing...
Nonalcoholic steatohepatitis (NASH) cirrhosis is the fastest growing indication for liver transplantation (LT) in United States. We aimed to determine temporal trend behind rise obesity and NASH‐related additions LT waitlist States make projections future NASH burden on waitlist. used data from Organ Procurement Transplantation Network database 2000 2014 obtain number of additions. The obese population was estimated using U.S. Census Bureau National Health Nutrition Examination Survey. Based...
Background: Metastasis and recurrence are the main causes of death from cervical cancer (CC), thus it is important to identify more effective biomarkers improve its prognosis. The purpose our research was determine potential role autophagy-related long non-coding RNA (lncRNA) in CC construct an lncRNA signature for survival CC. Methods: lncRNAs were downloaded Cancer Genome Atlas (TCGA) database, identified through co-expression genes autophagy genes. Several with prognostic value...
Objective To explore the ability of PAX1 methylation (PAX1 m ) to predict pathological upgrade cervical intraepithelial neoplasia (CIN) before cold knife conization (CKC). Methods A total 218 women that underwent colposcopy-directed biopsy (CDB) pathology for confirmation CIN2 and CIN3 between December 2020 September 2021 were enrolled in this study. The levels (ΔCp determined by quantitative methylation-specific polymerase chain reaction (qMSP). Receiver operating characteristic curve was...
Twelve laboratories representing 4 countries participated in an interlaboratory study conducted to determine all-trans-veta-carotene and total beta-carotene dietary supplements raw materials. Thirteen samples were sent as blind duplicates the collaborators. Results obtained from 11 are reported. For products composed softgels tablets that analyzed for beta-carotene, reproducibility relative standard deviation (RSDR) ranged 3.35 23.09% HorRat values 1.06 3.72. these trans 4.28 22.76% 0.92...
A novel concept is reported for carrying out the chemoenzymatic synthesis of an AB-type diblock copolymer without intermediate transformation step through combination enzymatic self-condensation polymerization and atom transfer radical (ATRP). Biocatalyst Novozyme 435 was first applied to catalyze 2,2,2-trichloroethyl 10-hydroxydecanate. The resulting CCl3-terminated polyester subsequently employed in ATRP styrene afford well-defined poly(2,2,2-trichloroethyl 10-hydroxydecanate)-block-polystyrene.
Objective: This study aims to analyze factors associated with lymphovascular space invasion (LVSI) and evaluate the prognostic significance of LVSI in Chinese endometrioid endometrial cancer (EEC) patients.Methods: Five-hundred eighty-four EEC patients undergoing surgery our center from 2006 2016 were selected for analysis.Univariate analysis multivariate logistic regression used examine relevant LVSI.To role LVSI, survival analyses conducted.In analyses, both Cox propensity score matching...
TPS8613 Background: Brentuximab vedotin (ADCETRIS), a CD30-targeted antibody-drug conjugate, has been approved for adults with relapsed or refractory CD30+ HL in 39 countries including the US and Europe. Front-line ABVD achieves complete response (CR) rates of 70–80% patients (pts) advanced HL. However, 10–20% pts are to front-line treatment an additional ≤25% relapse. Further, bleomycin-induced pulmonary toxicity occurs 10–25% (Horning, J Clin Oncol 1994). In post-autologous stem cell...
To establish a model for predicting adverse outcomes in advanced-age pregnant women with preterm preeclampsia China.We retrospectively collected the medical records of 896 who were older than 35 years and delivered at Affiliated Hospital Qingdao University from June 2018 to December 2020. The divided into an outcome group non-adverse according occurrence outcomes. data training set verification ratio 8:2. A nomogram was developed binary logistic regression created predict preeclampsia. ROC...
Abstract Buffalo is considered short‐day breeder in tropical and subtropical part of the world seasonality photoperiodism impart major influence on its fertility. However, impact vitro embryo production (IVEP) remains elusive. Therefore, this study investigated effect seasonal variations morphological molecular parameters IVEP buffalo. For purpose, we conducted two different experiments oocytes obtained by aspirating follicles from abattoir derived ovaries. In Exp. I, retrospective analysis...
Background The Cancer Genome Atlas (TCGA) project shed light on the vital role of tumor molecular features in predicting endometrial cancer patients’ prognosis. This study aims to investigate survival impact surgical approaches patients with different genetic alterations. Methods 473 from TCGA database were selected. To analyze prognostic approach, analyses conducted features. Finally, a simplified stratification model was established select suitable for open or minimally invasive surgery...
10028 Background: Brentuximab vedotin (ADCETRIS) is a novel antibody-drug conjugate that targets CD30, cell surface antigen expressed by HL and sALCL. The ph 1 portion of this study evaluated safety, pharmacokinetics (PK), recommended 2 dose (RP2D) brentuximab in pediatric pts with RR CD30-expressing tumors. Methods: Ph 1/2, open-label, multicenter aged to <18 years or sALCL (5 for HL). Pts received IV infusion once every 21 days (Q3wk). start was 1.4 mg/kg escalated 1.8 traditional 3+3...
4656 Background: The investigational agent orteronel (ortl, TAK-700) is a selective 17,20-lyase inhibitor that blocks androgen production. Since DP standard chemotherapy in mCRPC, this phase 1/2 study examined ortl + men with mCRPC. Methods: primary I objective was to determine the maximum dose of 200–400 mg BID can be administered safely castrate (testosterone [T] <50 ng/dL) ≤1 prior and no ketoconazole/abiraterone ≤30 d prior. A 3+3 escalation used 200 then 400 BID. Ortl dosed daily D...
This study assessed the predictive value of metabolic risk score (MRS) for lymphovascular space invasion (LVSI) in endometrial cancer (EC) patients.