Gabriella Verucchi
A5042900908- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- HIV/AIDS drug development and treatment
- Liver Disease and Transplantation
- HIV-related health complications and treatments
- HIV Research and Treatment
- HIV/AIDS Research and Interventions
- Hepatitis Viruses Studies and Epidemiology
- Liver Diseases and Immunity
- Systemic Lupus Erythematosus Research
- COVID-19 Clinical Research Studies
- Drug-Induced Hepatotoxicity and Protection
- Blood groups and transfusion
- Parvovirus B19 Infection Studies
- SARS-CoV-2 and COVID-19 Research
- Diabetes and associated disorders
- Pneumocystis jirovecii pneumonia detection and treatment
- Cytomegalovirus and herpesvirus research
- Herpesvirus Infections and Treatments
- Gallbladder and Bile Duct Disorders
- Hepatocellular Carcinoma Treatment and Prognosis
- Biliary and Gastrointestinal Fistulas
- Pediatric Hepatobiliary Diseases and Treatments
- Parasites and Host Interactions
University of Bologna
2015-2025
Policlinico S.Orsola-Malpighi
2014-2024
Regione Emilia-Romagna
2023
Agenzia Sanitaria e Sociale Regionale
2023
ORCID
2020
Azienda Ospedaliera San Gerardo
2019
ASST Fatebenefratelli Sacco
2019
Italian Medicines Agency
2018
Azienda USL di Bologna
2016-2017
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2016
Abstract Background We evaluated the incidence of invasive pulmonary aspergillosis among intubated patients with critical COVID-19 and different case definitions aspergillosis. Methods Prospective, multicenter study in adult microbiologically confirmed receiving mechanical ventilation. All included participants underwent a screening protocol for bronchoalveolar lavage galactomannan cultures performed on admission at 7 days clinical deterioration. Cases were classified as...
We investigated the significance of microbial translocation measured on average 3 years after HIV seroconversion in driving disease progression untreated patients with high CD4(+) cell count.We included ICONA documented last HIV-negative and first HIV-positive test, at least one plasma sample stored while antiretroviral therapy (ART)-naive count greater than 200 cells/μl.Microbial [lipopolysaccharide (LPS), sCD14 EndoCAb] immune activation (IL-6 TNF-α) were measured. Correlation between...
Abstract Background & Aims Despite the excellent efficacy of direct‐acting antivirals ( DAA ) reported in clinical trials, virological failures can occur, often associated with development resistance‐associated substitutions RAS s). This study aimed to characterize presence clinically relevant s all classes real‐life failures. Methods Of 200 that were analyzed 197 ‐treated patients, 89 pegylated‐interferon+ribavirin (Peg IFN + RBV and 111 without HCV ‐1a/1b/1g/2/3/4=58/83/1/6/24/25;...
The impact on patient survival of an infectious disease (ID) team dedicated to the early management severe sepsis/septic shock (SS/SS) in Emergency Department (ED) has yet be assessed.A quasiexperimental pre-post study was performed at general ED our hospital. During pre phase (June 2013-July 2014), all consecutive adult patients with SS/SS were managed according standard care, data prospectively collected. post (August 2014-October 2015), collaboration a ID performing bedside evaluation...
The safety and efficacy of sofosbuvir-velpatasvir in children aged 3-17 years with chronic hepatitis C virus (HCV) infection any genotype were evaluated.
Abstract Background Since the end of February 2020, Coronavirus Disease 2019 (COVID-19) outbreak rapidly spread throughout Italy and other European countries, but limited information has been available about its characteristics in HIV-infected patients. Methods We have described a case series patients with HIV infection COVID-19 diagnosed at S.Orsola Hospital (Bologna, Italy) during March April, 2020. Results reported 26 COVID-19. Nineteen subjects were men, median age was 54 years, 73% had...
Background: Autoimmune hepatitis (AIH) has three different presentations: chronic, acute and asymptomatic.
Abstract Background We analyzed the impact of continuous/extended infusion (C/EI) vs intermittent piperacillin-tazobactam (TZP) and carbapenems on 30-day mortality patients with liver cirrhosis bloodstream infection (BSI). Methods The BICRHOME study was a prospective, multicenter that enrolled 312 cirrhotic BSI. In this secondary analysis, we selected receiving TZP or as adequate empirical treatment. C/EI assessed Kaplan-Meier curves, Cox-regression model, estimation average treatment effect...
The study measures trends in the profile of patients with chronic hepatitis B virus linked to care Italy.A cross-sectional, multicenter, observational cohort (PITER cohort) consecutive surface antigen (HBsAg) over period 2019-2021 from 46 centers was evaluated. reference MASTER collected years 2012-2015. Standard statistical methods were used.The PITER enrolled 4583 patients, whom 21.8% non-Italian natives. Compared those MASTER, older and more often female. prevalence e (HBeAg) declined...
Background and aimsSevere liver disease markers assessed before HCV eradication are acknowledged to usually improve after the SVR. We prospectively evaluated, in PITER cohort, long-term HCC risk profile based on predictors monitored by direct-acting antivirals patients with cirrhosis.MethodsHCC occurrence was evaluated Kaplan-Meier analysis. Cox regression analysis identified post-treatment variables associated de-novo HCC; their predictive power presented a nomogram.ResultsAfter end of...
Mixed cryoglobulinemia is the most common HCV extrahepatic manifestation. We aimed to prospectively evaluate cryoglobulinemic vasculitis (CV) clinical profile after a sustained virologic response (SVR) over medium-term long-term period.
We evaluated the prevalence and clinical significance of non-organ-specific autoantibodies (NOSAs) in 47 hepatitis C virus (HCV)-positive children with abnormal alanine transaminase levels analyzed association between NOSAs level, genotype, human leukocyte antigen status, interferon (IFN) response. Forty-two B (HBV)-positive 25 age- sex-matched healthy served as control subjects. were found 34% HCV-positive children, 12% HBV-positive controls, none Liver-kidney microsomal antibody type 1...