A5045667573- Cancer survivorship and care
- Childhood Cancer Survivors' Quality of Life
- Cancer-related cognitive impairment studies
- Family Support in Illness
- Palliative Care and End-of-Life Issues
- CAR-T cell therapy research
- Hematopoietic Stem Cell Transplantation
- Glioma Diagnosis and Treatment
- Economic and Financial Impacts of Cancer
- Cancer Treatment and Pharmacology
- Brain Metastases and Treatment
- Lung Cancer Treatments and Mutations
- Head and Neck Cancer Studies
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Sleep and related disorders
- Dementia and Cognitive Impairment Research
- COVID-19 and healthcare impacts
- Nutrition and Health in Aging
- Mobile Health and mHealth Applications
- Multiple Myeloma Research and Treatments
- Pain Management and Opioid Use
- Renal cell carcinoma treatment
- Lung Cancer Research Studies
Moffitt Cancer Center
2016-2025
University of South Florida
2009-2024
Stanford University
2023
Comprehensive Blood & Cancer Center
2023
Hospital Universitario San Ignacio
2023
Roche (Sweden)
2020
Janssen (Belgium)
2018-2020
Janssen (Switzerland)
2020
Janssen Scientific Affairs (United States)
2020
Jimma University
2019
Background Defective cellular transport processes can lead to aberrant accumulation of trace elements, iron, small molecules and hormones in the cell, which turn may promote formation reactive oxygen species, promoting DNA damage expression key regulatory cancer genes. As uncontrolled proliferation are hallmarks cancer, including epithelial ovarian (EOC), we hypothesized that inherited variation genes contributes EOC risk. Methods In total, samples were obtained from 14,525 case subjects...
Men receiving androgen-deprivation therapy (ADT) for prostate cancer may be at risk cognitive impairment; however, evidence is mixed in the existing literature. Our study examined impact of ADT on impaired performance and explored potential demographic genetic predictors performance.Patients with were assessed before or within 21 days starting (n = 58) 6 12 months later. Age- education-matched patients treated prostatectomy only 84) men without 88) similar intervals. Participants provided...
Patients with cancer typically have greater financial hardships and time costs than individuals without cancer. The COVID-19 pandemic has exacerbated this, while posing substantial challenges to delivering care resulting in important changes care-delivery models, including the rapid adoption of telehealth.To estimate patient travel, time, cost savings associated telehealth for delivery.An economic evaluation from completed visits April 1, 2020, June 30, 2021, a single-institution National...
The authors investigated the relationship between stress at initial cancer diagnosis and treatment subsequent quality of life (QoL). Women (n = 112) randomized to assessment-only arm a clinical trial were initially assessed after breast surgery then reassessed 4 months (during adjuvant treatment) 12 (postadjuvant treatment). There 3 types measured: number stressful events (K. A. Matthews et al., 1997), cancer-related traumatic symptoms (M. J. Horowitz, N. Wilner, & W. Alvarez, 1979),...
The search for meaning in life is part of the human experience. A negative event may threaten perceptions about life, such as benevolence world and one's sense harmony peace. authors examined longitudinal relationship between women's coping with a diagnosis breast cancer their self-reported 2 years later. Multiple regression analyses revealed that positive strategies predicted significant variance life--feelings inner peace, satisfaction current future, spirituality faith--and absence...
Abstract BACKGROUND: Recent attention has focused on the negative effects of chemotherapy cognitive performance cancer survivors. The current study examined modification this risk by catechol‐O‐methyltransferase (COMT) genotype based evidence in adult populations that presence a Val allele is associated with poorer performance. METHODS: Breast survivors treated radiotherapy (n = 58), and/or 72), and 204 healthy controls (HCs) completed tests provided saliva for COMT genotyping. was divided...
Mindfulness-based stress reduction (MBSR) reduces symptoms of depression, anxiety, and fear recurrence among breast cancer (BC) survivors. However, the effects MBSR on telomere length (TL) telomerase activity (TA), known markers cellular aging, psychological stress, disease risk, are not known. This randomized, wait-listed, controlled study, nested within a larger trial, investigated TL TA. BC patients (142) with Stages 0–III who had completed adjuvant treatment radiation and/or chemotherapy...
To determine treatment and aging-related effects on longitudinal cognitive function in older breast cancer survivors.
Epithelial ovarian cancer (EOC) has a heritable component that remains to be fully characterized. Most identified common susceptibility variants lie in non-protein-coding sequences. We hypothesized the 3′ untranslated region at putative microRNA (miRNA)-binding sites represent functional targets influence EOC susceptibility. Here, we evaluate association between 767 miRNA-related single-nucleotide polymorphisms (miRSNPs) and risk 18,174 cases 26,134 controls from 43 studies genotyped through...
The purpose of this study was to investigate the effects mindfulness-based stress reduction for breast cancer survivors (MBSR(BC)) on multiple measures objective and subjective sleep parameters among (BCS).Data were collected using a two-armed randomized controlled design BCS enrolled in either 6-week MBSR(BC) program or usual care (UC) group with 12-week follow-up. present analysis is subset larger parent trial (ClinicalTrials.gov Identifier: NCT01177124). Seventy-nine participants (mean...
The coronavirus disease 2019 (COVID-19) pandemic has had wide-ranging health effects and increased isolation. Older with cancer patients might be especially vulnerable to loneliness poor mental during the pandemic.The authors included active participants enrolled in longitudinal Thinking Living With Cancer study of nonmetastatic breast survivors aged 60 89 years (n = 262) matched controls 165) from 5 US regions. Participants completed questionnaires at parent enrollment then annually,...