Lixin Shi

ORCID: 0000-0002-5777-8660
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About
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Research Areas
  • Thyroid Disorders and Treatments
  • Renal cell carcinoma treatment
  • Bone health and osteoporosis research
  • Adipose Tissue and Metabolism
  • Thyroid Cancer Diagnosis and Treatment
  • Vitamin D Research Studies
  • Cancer-related molecular mechanisms research
  • Growth Hormone and Insulin-like Growth Factors
  • Pediatric Urology and Nephrology Studies
  • Bladder and Urothelial Cancer Treatments
  • Ureteral procedures and complications
  • Urological Disorders and Treatments
  • RNA Research and Splicing
  • Minimally Invasive Surgical Techniques
  • Circular RNAs in diseases
  • MicroRNA in disease regulation
  • Folate and B Vitamins Research
  • RNA modifications and cancer
  • Fatty Acid Research and Health
  • Adipokines, Inflammation, and Metabolic Diseases
  • Electrochemical sensors and biosensors
  • Eicosanoids and Hypertension Pharmacology
  • Sleep and related disorders
  • Sleep and Wakefulness Research
  • Nutritional Studies and Diet

Nanyang Medical College
2012-2025

West China Hospital of Sichuan University
2025

Sichuan University
2025

Zhengzhou Children's Hospital
2023

Zhengzhou University
2023

Guiyang Medical University
2017-2021

Affiliated Hospital of Guizhou Medical University
2017-2021

Chinese PLA General Hospital
2008-2017

People's Liberation Army No. 150 Hospital
2013

Hangzhou Academy of Agricultural Sciences
2008

The goal of eliminating iodine deficiency worldwide was successfully achieved in China after the implementation a mandatory universal salt iodization program for last 16 years. Thus, has been assessed as country with more than adequate levels. This survey aimed to investigate current status and effects an increased intake on spectrum prevalence thyroid disorders.A total 15,008 adult subjects from 10 cities eastern central were investigated. Serum thyrotropin (TSH), peroxidase antibodies...

10.1089/thy.2015.0613 article EN Thyroid 2016-07-02

Background Non-coding circular RNAs (circRNAs) have displayed dysregulated expression in several human cancers. Here, we profiled the circRNA of papillary thyroid carcinoma (PTC) tumors to improve our understanding PTC pathogenesis. Methods Microarray profiling was performed on 18 samples, consisting six tumors, matching contralateral normal and benign lesions. After low-intensity filtering, hierarchical clustering revealed patterns. Statistical analysis followed by qRT-PCR validation...

10.1371/journal.pone.0170287 article EN cc-by PLoS ONE 2017-03-13

Background: The fact that serum thyrotropin (TSH) levels increase with age may influence the diagnosis of thyroid diseases in older adults. This study aimed to establish an age-specific TSH reference range, examine prevalence adults ≥65 years, and analyze risk factors. Methods: A cross-sectional adult populations 10 cities China was conducted from 2010 2011. total 15,008 subjects were randomly selected completed present study. Urinary iodine concentration, TSH, peroxidase antibody (TPOAb),...

10.1089/thy.2017.0715 article EN Thyroid 2018-10-23

Background The triglyceride glucose (TyG) index has been associated with an increased risk in breast cancer. However, this association remains unclear among the Chinese population. This study aimed to investigate whether TyG is of prevalent cancer women. Methods cross-sectional included 142,184 women from REACTION (Risk Evaluation Cancers Diabetic Individuals: A Longitudinal) Study, which recruited adults aged 40 years or older 25 centers across mainland China between 2011 and 2012. was...

10.3389/fendo.2024.1321622 article EN cc-by Frontiers in Endocrinology 2024-06-06

Abstract Previous studies suggested that fecal short-chain fatty acids (SCFAs) and branched (BCFAs) are associated with glucose regulation. However, the potential relationship between circulating SCFAs BCFAs incident diabetes risk in both men women remains unidentified prospective cohort studies. In this study, we examined a panel of nine serum 3414 subjects diabetes, matched normoglycemic controls from China Cardiometabolic Disease Cancer Cohort study. fully adjusted conditional logistic...

10.1093/lifemeta/loaf001 article EN cc-by Life Metabolism 2025-01-22

Abstract Aims To determine the impact of body roundness index (BRI) on 10‐year risk cardiovascular disease (CVD) and all‐cause mortality in Chinese adults. Materials Methods We utilized data from a nationwide prospective cohort 165 785 adults (aged ≥40 years, free CVD cancer at baseline), which was extracted China Cardiometabolic Disease Cancer Cohort (4C). Cox regression restricted cubic splines quantified BRI‐outcome associations identified optimal BRI cutoffs. Results During median...

10.1111/dom.16272 article EN Diabetes Obesity and Metabolism 2025-02-19

A 60-year-old male was diagnosed with bipolar II disorder 30 years before the current visit (Figure 1). During that 30-year period, he hospitalized four times and received various pharmaceutical treatments. The patient's condition stabilized after use of Depakin quetiapine for previous 7 years. One week visit, patient cervical spondylosis, began to worry about his physical condition. He gradually developed symptoms such as depressed mood, lack motivation, social withdrawal. His worsened 1...

10.1111/bdi.70024 article EN Bipolar Disorders 2025-03-18

Abstract Aims Few studies have analysed the effect of sleep duration and snoring on hypertension glycaemic control in patients with diabetes. This study aims to investigate relationship prevalent people Methods In baseline survey REACTION study, 56 032 diabetes were categorized into four groups according self‐reported duration: < 6, 6–7.9, 8–8.9 ≥ 9 h. Snoring frequency was evaluated as ‘usually’, ‘occasionally’ or ‘never’. Hypertension assessed by systolic blood pressure, diastolic...

10.1111/dme.12809 article EN Diabetic Medicine 2015-05-20

We describe here a new approach to construct multilayer enzyme/polyelectrolyte film on structured transparent indium−tin oxide (ITO) covered glass electrode surface as micropattern, which two different types of enzyme distributed laterally one common substrate without interference. The was prepared by alternate electric field directed layer-by-layer assembly deposition and redox enzymes polyelectrolyte poly(diallyldimethylammonium chloride) (PDDA) onto the site-selective ITO surface. cyclic...

10.1021/bm030003e article EN Biomacromolecules 2003-08-06

The effects of supplementing a barley-based diet for weaned piglets withexogenous beta-glucanase and xylanase on gastrointestinal digestiveenzyme activities were investigated. Thirty-six cross-bred pigletswere randomly assigned to two groups with three pens based sexand mass. Each group was fed the barley or withoutadded (0.15%) 4-week period. Theresults showed that enzyme supplementation improved growth performanceof significantly (p < 0.05), but had no effect = 0.091)on average daily feed...

10.1111/j.1439-0396.2008.00816.x article EN Journal of Animal Physiology and Animal Nutrition 2008-05-19

Exportin 5 (XPO5) is a microRNA (miRNA)-related nuclear export protein, and its disorder may lead to the dysregulation of miRNAs. Recent studies have demonstrated that aberrant expression XPO5 might participate in carcinogenesis certain cancers. However, there only limited information thyroid cancer (TC) development. In our study, we quantified level by real-time polymerase chain reaction (PCR) 64 TC patients' tissues adjacent normal tissues. After confirming expression, evaluated...

10.1097/md.0000000000006351 article EN cc-by-nc Medicine 2017-04-01

Background: Long noncoding RNA MALAT1 has been previously reported in the carcinogenesis of several tumors, and its potential functional polymorphisms have also investigated various diseases. However, relationship between these susceptibility thyroid cancer still largely unknown. In present study, we aimed to explore association (TC) susceptibility, as well biological function TC. Methods: We conducted a case-control study with 1134 papillary (PTC) patients 1228 controls evaluate correlation...

10.7150/jca.28887 article EN cc-by-nc Journal of Cancer 2019-01-01

To report our experience of pure laparoscopic and robot-assisted reconstructive surgery in congenital megaureter, seven patients (one bilateral) with symptomatic megaureter underwent or surgery. The was exposed at the level blood vessel isolated to bladder narrow area. Extreme ureter trim submucosal tunnel encapsulation papillary implantations anti-reflux anastomosis were performed intraperitoneally by clinical data after operation analyzed, including time, intraoperative complications,...

10.1371/journal.pone.0099777 article EN cc-by PLoS ONE 2014-06-12

Abstract Background Irisin is a novel myokine associated with obesity, which traditional cardiovascular risk factor (CVRF). The present study aimed to investigate the association between serum irisin and single CVRF as well clustering of CVRFs among Chinese overweight/obese population. Methods A total 98 overweight 93 obese subjects without clinical treatments were enrolled in this study. Subjects then divided into two groups, based on level: low group (1.10–13.44 ng/ml) high (13.49–29.9...

10.1186/s12872-021-02380-0 article EN cc-by BMC Cardiovascular Disorders 2021-11-30

Background. Associations between iodine intake and thyroid nodules (TNs) were not consistent. We aimed to illustrate the relationship urinary concentration (UIC) TNs. Methods. A total of 12,698 participants enrolled in analysis. All filled out questionnaires underwent physical examinations, laboratory tests, ultrasonography. UIC, serum thyrotropin (TSH), peroxidase antibodies (TPOAb), thyroglobulin (TgAb) measured central laboratory. Results. The prevalence TNs was 16.00%, median UIC 206.1...

10.1155/2020/4138657 article EN cc-by BioMed Research International 2020-12-17

In this report, we describe the effect of conjugating o-carborane-C(1)C(2)-dicarboxylic acid (o-C2B10H10-C2O4H2, denoted as Cbac2) to cadmium telluride quantum dots (CdTe QDs) capped with cysteamine on photophysics and cytotoxicity QDs. Cbac2 quenches fluorescence intensity induces a red shift emission peak. Meanwhile, studies real time cell electronic sensing (RT-CES) system 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl (MTT) assay indicate that combination carborane carboxylic derivative...

10.1166/jnn.2011.3603 article EN Journal of Nanoscience and Nanotechnology 2011-03-14

To introduce a low-cost, self-made device for single-port retroperitoneal laparoscopic radical nephrectomy and to evaluate outcomes compared with conventional laparoscopy after initial experience using this device.Twenty-nine renal cancer patients underwent laparoendoscopic single-site multiple manipulation channels passage of routine instruments specimen removal. A control group 29 who were matched by age, gender, stage laparoscopy. Outcomes analyzed retrospectively.There no significant...

10.1177/1553350612460768 article EN Surgical Innovation 2012-12-04

Irisin, a newly discovered myokine, exerts beneficial effects on energy metabolism. However, published results from studies examining the relationship between irisin concentration and obesity have been conflicting. The aim of our study was to investigate association serum level obese individuals with different body mass index (BMI) values explore question whether can predict risk increases in BMI. This based data collected Risk Evaluation cAncers Chinese diabeTic Individuals: lONgitudinal...

10.1007/s13300-019-0588-4 article EN cc-by-nc Diabetes Therapy 2019-02-27

To evaluate the feasibility and outcomes of retroperitoneal laparoscopic nephrotomy along Brodel line tumor enucleation (TE) for complete intraparenchymal renal tumors.We retrospectively analyzed medical charts patients with endophytic tumors who underwent TE between 2012 2015. Perioperative data, surgical technique, pathologic variables, complications, functional, oncologic were reviewed.Twenty-one (mean age 50 years; mean body mass index 25.8 kg/m2) treated incision. The size was 2.0 cm,...

10.1089/end.2017.0236 article EN Journal of Endourology 2017-07-27

To explore the potential role of irisin in outcomes newly diagnosed prediabetes.

10.1111/jdi.13416 article EN cc-by-nc-nd Journal of Diabetes Investigation 2020-10-01
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