Pauline Favre
A5031696705- Functional Brain Connectivity Studies
- Bipolar Disorder and Treatment
- Advanced Neuroimaging Techniques and Applications
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Psychosomatic Disorders and Their Treatments
- Mental Health Research Topics
- Health, Environment, Cognitive Aging
- Neurological disorders and treatments
- Mindfulness and Compassion Interventions
- Healthcare Decision-Making and Restraints
- Schizophrenia research and treatment
- Neural and Behavioral Psychology Studies
- Electroconvulsive Therapy Studies
- Health, Medicine and Society
- Psychoanalysis and Psychopathology Research
- Attention Deficit Hyperactivity Disorder
- Advanced MRI Techniques and Applications
- Transcranial Magnetic Stimulation Studies
- Electrolyte and hormonal disorders
- Fetal and Pediatric Neurological Disorders
- Genetic Syndromes and Imprinting
- Child and Adolescent Psychosocial and Emotional Development
- Vestibular and auditory disorders
- Epilepsy research and treatment
- Genetic Associations and Epidemiology
CEA Paris-Saclay
2018-2024
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2018-2024
Université Paris-Saclay
2019-2024
Université Paris-Est Créteil
2020-2024
Inserm
2018-2024
NeuroSpine Institute
2020-2023
Fondation FondaMental
2019-2023
Assistance Publique – Hôpitaux de Paris
2020-2023
Université Grenoble Alpes
2013-2023
Centre Hospitalier Universitaire de Grenoble
2016-2023
Abstract Major depressive disorder (MDD) is associated with an increased risk of brain atrophy, aging-related diseases, and mortality. We examined potential advanced aging in adult MDD patients, whether this process clinical characteristics a large multicenter international dataset. performed mega-analysis by pooling measures derived from T1-weighted MRI scans 19 samples worldwide. Healthy was estimated predicting chronological age (18–75 years) 7 subcortical volumes, 34 cortical thickness...
Discrete yet overlapping frontal-striatal circuits mediate broadly dissociable cognitive and behavioural processes. Using a recently developed multi-echo resting-state functional MRI (magnetic resonance imaging) sequence with greatly enhanced signal compared to noise ratios, we map frontal cortical projections the striatum striatal through direct indirect basal ganglia circuit. We demonstrate distinct limbic (ventromedial prefrontal regions, ventral – VS, tegmental area VTA), motor...
Abstract The ENIGMA‐DTI (diffusion tensor imaging) workgroup supports analyses that examine the effects of psychiatric, neurological, and developmental disorders on white matter pathways human brain, as well normal variation its genetic associations. seven ENIGMA disorder‐oriented working groups used workflow to derive patterns deficits using coherent coordinated model disease across cohorts worldwide. This yielded largest studies detailing in schizophrenia spectrum disorder (SSD), bipolar...
Abstract Background Major depressive disorder (MDD) is associated with an increased risk of brain atrophy, aging-related diseases, and mortality. We examined potential advanced aging in MDD patients, whether this process clinical characteristics a large multi-center international dataset. Methods performed mega-analysis by pooling measures derived from T1-weighted MRI scans 29 samples worldwide. Normative was estimated predicting chronological age (10-75 years) 7 subcortical volumes, 34...
Abstract Emotion dysregulation is central to the development and maintenance of psychopathology, common across many psychiatric disorders. Neurobiological models emotion involve fronto-limbic brain network, including in particular amygdala prefrontal cortex (PFC). Neural variability has recently been suggested as an index cognitive flexibility. We hypothesized that within-subject neural network would be related inter-individual variation context low affective control. In a multi-site cohort...
Background Patients with bipolar disorder experience cognitive and emotional impairment that may persist even during the euthymic state of disease. These persistent symptoms in patients (BP) be characterized by disturbances emotion regulation related fronto-limbic brain circuitry. The present study aims to investigate modulation activity connectivity BP processing conflict. Methods Fourteen 13 matched healthy subjects (HS) underwent functional magnetic resonance imaging (fMRI) while...
This review summarizes the last decade of work by ENIGMA (Enhancing NeuroImaging Genetics through Meta Analysis) Consortium, a global alliance over 1,400 scientists across 43 countries, studying human brain in health and disease. Building on large-scale genetic studies that discovered first robustly replicated loci associated with metrics, has diversified into 50 working groups (WGs), pooling worldwide data expertise to answer fundamental questions neuroscience, psychiatry, neurology,...
Brain sulcation is an indirect marker of neurodevelopmental processes. Studies the cortical in bipolar disorder have yielded mixed results, probably due to high variability clinical phenotype. We investigated whole-brain a large sample selected patients with load.A total 263 I and 320 controls were included multicentric magnetic resonance imaging (MRI) study. All subjects underwent high-resolution T1-weighted brain MRI. Images processed automatized pipeline extract global sulcal index (g-SI)...
The cerebellum is involved in cognitive processing and emotion control. Cerebellar alterations could explain symptoms of schizophrenia spectrum disorder (SZ) bipolar (BD). In addition, literature suggests that lithium might influence cerebellar anatomy. Our aim was to study anatomy SZ BD, investigate the effect lithium.Participants from 7 centers worldwide underwent a 3T MRI. We included 182 patients with SZ, 144 322 controls. automatically segmented using CERES pipeline. All outputs were...
Lithium (Li) is the gold standard treatment for bipolar disorder (BD). However, its mechanisms of action remain unknown but include neurotrophic effects. We here investigated influence Li on cortical and local grey matter (GM) volumes in a large international sample patients with BD healthy controls (HC).We analyzed high-resolution T1-weighted structural magnetic resonance imaging scans 271 type I (120 undergoing Li) 316 HC. Cortical GM were compared using voxel-wise approaches voxel-based...
<b><i>Background:</i></b> MRI studies in patients with bipolar disorder have suggested that lithium is associated grey matter increases may underlie its therapeutic effects. However, the relationship between volume and cellular microstructural changes not straightforward, as modifications of different compartments be involved. <b><i>Objectives:</i></b> Our aim was to test hypothesis dendritic density higher undergoing therapy than without...