A5115589840- Cervical Cancer and HPV Research
- Genital Health and Disease
- Endometrial and Cervical Cancer Treatments
- Reproductive tract infections research
- Hepatitis B Virus Studies
- Global Cancer Incidence and Screening
- Cancer-related molecular mechanisms research
- Image Enhancement Techniques
- Water Quality Monitoring Technologies
- Lung Cancer Treatments and Mutations
- Remote Sensing and LiDAR Applications
- Neuroendocrine Tumor Research Advances
- Molecular Biology Techniques and Applications
- Neuroblastoma Research and Treatments
- MicroRNA in disease regulation
- Lung Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Meningioma and schwannoma management
- Viral-associated cancers and disorders
- Lung Cancer Research Studies
- Glioma Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Immunotherapy and Immune Responses
- Liver Disease Diagnosis and Treatment
- Magnesium Alloys: Properties and Applications
Shanghai Jiao Tong University
2024-2025
Anhui Business College
2025
Zhejiang University of Technology
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2015-2024
Qinghai University
2024
Changhai Hospital
2024
Second Military Medical University
2024
Zhejiang Chinese Medical University
2024
Harbin Institute of Technology
2024
China University of Mining and Technology
2024
Background Rapid ventricular pacing leads to a cardiac myopathy consisting of an increase in chamber dimension, mural thinning, elevation wall stress, and congestive heart failure, mimicking dilated cardiomyopathy humans. However, contrasting results have been obtained concerning the mechanisms dilation existence myocardial hypertrophy. Moreover, questions raised regarding occurrence damage cell loss development experimental myopathy. Methods Results The functional structural characteristics...
Background: Combinations of aspirin with thienopyridine derivatives (clopidogrel bisulfate or ticlopidine hydrochloride) and/or warfarin sodium are increasingly being used in various cardiac conditions.However, little is known about the bleeding risks associated these combinations, particularly elderly individuals at population level.This study estimates combinations aspirin, derivatives, and patients. Methods:We conducted a population-based observational cohort using linked administrative...
Abstract High‐risk (HR) human papillomavirus (HPV) prevalence has been shown to correlate well with cervical cancer incidence rates. Our study aimed estimate the of HR‐HPV and intraepithelial neoplasia (CIN) in China indirectly informs on burden country. A total 30,207 women from 17 population‐based studies throughout were included. All received HPV DNA testing (HC2, Qiagen, Gaithersburg, MD), visual inspection acetic acid liquid‐based cytology. Women positive for any test...
The objective of this study was to assess the long-term effects breastfeeding on child behavior and maternal adjustment.We followed up children who were in Promotion Breastfeeding Intervention Trial, a cluster-randomized trial promotion intervention based World Health Organization/United Nations Children's Fund Baby-Friendly Hospital Initiative. A total 17,046 healthy, mother-infant pairs enrolled from 31 Belarussian maternity hospitals affiliated polyclinics; 13,889 (81.5%) at 6.5 years....
Abstract Background The high cost and insufficient supply of human papillomavirus (HPV) vaccines have slowed the pace controlling cervical cancer. A phase III clinical trial was conducted to evaluate efficacy, safety, immunogenicity a novel Escherichia coli-produced bivalent HPV-16/18 vaccine. Methods multicenter, randomized, double-blind started on November 22, 2012 in China. In total, 7372 eligible women aged 18–45 years were age-stratified randomly assigned receive three doses test or...
Abstract Small cell lung cancer (SCLC) is one of the most aggressive types cancer, yet pathologic mechanisms underlying its devastating clinical outcome remain elusive. In this report, we surveyed 924 miRNA (miR) for their expressions in formalin-fixed paraffin-embedded specimens from 42 patients with SCLC, and found that downregulated miR-886-3p closely correlated shorter survival SCLC. This correlation was validated another 40 cases. It further discovered loss expression mediated by DNA...
The objectives of this study were to compare the sensitivity colposcopically directed biopsy (biopsy cervical quadrants with colposcopic impressions human papillomavirus, intraepithelial neoplasia [CIN], or cancer) for CIN 3 cancer (CIN 3+) among physicians and estimate increase in yield 3+ per colposcopy associated "random" biopsies and/or endocervical curettage (ECC).Two studies which 7 performed 1,383 examinations on women abnormal cytology reviewed. At colposcopy, cervix was divided into...
Abstract Background Colposcopy diagnosis and directed biopsy are the key components in cervical cancer screening programs. However, their performance is limited by requirement for experienced colposcopists. This study aimed to develop validate a Colposcopic Artificial Intelligence Auxiliary Diagnostic System (CAIADS) grading colposcopic impressions guiding biopsies. Methods Anonymized digital records of 19,435 patients were obtained from six hospitals across China. These included images,...
Abstract Gain of chromosome 11q13 is a common event in esophageal squamous cell carcinoma (ESCC). The cortactin gene (CTTN, also EMS1), located at 11q13, plays pivotal role coupling membrane dynamics to cortical actin assembly. This has been implicated the motility several types cells. In present study, we found that amplification and overexpression CTTN was associated with lymph node metastasis ESCC. Functional analysis by small interfering RNA–mediated silencing revealed addition effect on...
Abstract New, lower-cost tests that target high-risk human papillomavirus (HR-HPV) have been developed for cervical cancer screening in lower-resource settings but large, population-based studies are lacking. Women ages 25 to 65 years and living rural China (n = 7,543) self-collected a cervicovaginal specimen, had 2 specimens collected by clinician, underwent visual inspection after acetic acid (VIA). The self- one clinician-collected HR-HPV DNA testing careHPV (QIAGEN) Hybrid Capture (HC2;...
Human Papillomavirus (HPV) is reported in 60-100% of cervical adenocarcinoma (CADC) globally. We investigated this relationship a hospital-based survey China. 718 CADC samples from nine Chinese regions were analysed. Expert pathologists reviewed cases with p16 and progesterone receptor immunostaining. Cases tested for HPV using whole-tissue sections (WTS) laser-capture microdissection. All HPV-tested by L1 based broad-spectrum SPF10 -DEIA-LiPA25 PCR. Negative DNA adequacy E6 oncogene,...
Cameras are deployed at scale with the purpose of searching and tracking objects interest (e.g., a suspected person) through camera network on live videos. Such cross-camera analytics is data compute intensive, whose costs grow number cameras time. We present Spatula, cost-efficient system that enables scaling edge boxes to large networks by leveraging spatial temporal correlations. While such correlations have been used in computer vision community, Spatula uses them drastically reduce...
p63 is a recently identified homologue of the tumor suppressor gene TP53, which encodes multiple isotypes with transactivating, death-inducing and dominant-negative activities. expressed in basal cells squamous epithelia many kinds tumors. To explore penetrance esophageal cancer, we analyzed expression cell carcinomas, adjacent dysplasia histologically normal mucosa esophagus by combination immunohistochemistry reverse transcriptase-polymerase chain reaction (RT-PCR). The results showed that...
Abstract Cervical cancer remains one of the leading causes death among women in developing countries. Without resources to support Pap smear cytology and colposcopy, cost-effective approaches which enable single-visit “see-and-treat” protocols offer potential reduce morbidity mortality due this preventable disease. We carried out a pilot clinical study Shanxi province, China, evaluate low-cost, high-resolution microendoscope (HRME) imaging system enables evaluation epithelial cell morphology...
p16(INK4A) is strongly expressed in tissues diagnosed as cervical intraepithelial neoplasia (CIN) and cancer women infected with human papillomavirus (HPV), but few prospective studies have evaluated a marker for the risk of low-grade CIN (CIN1) progression. We investigated prevalence immunostaining by grade whether overexpression CIN1 predicts future high-grade Chinese women. 6,557 aged 30-49 years were screened from 2003 to 2005 using cytology carcinogenic HPV test. Colposcopy was...
// Lu-Lu Yu 1 , Wen Chen Xiao-Qin Lei Qin Ze-Ni Wu Qin-Jing Pan 2 Xun Zhang Bai-Feng Chang Shao-Kai 3 Hui-Qin Guo and You-Lin Qiao Department of Cancer Epidemiology, Hospital, Chinese Academy Medical Sciences Peking Union College, Beijing, P. R. China Pathology, Henan Affiliated Hospital Zhengzhou University, Office for Control Research, Zhengzhou, Correspondence to: Guo, email: Qiao, Keywords : cervical cancer; p16/Ki-67 dual staining; human papillomavirus; women; Pathology Section Received...
Abstract Background Cervical cancer is a major public health concern in China. We report the end‐of‐study results of phase II/III trial to assess efficacy, immunogenicity, and safety AS04‐human papillomavirus (HPV)‐16/18 vaccine Chinese women aged 18‐25 years followed for up 72 months after first vaccination. Results approximately 57 following vaccination have been previously reported. Methods Healthy 18‐25‐year‐old (N = 6051) were randomized (1:1) receive three doses AS04‐HPV‐16/18 or...
Abstract Optical neural networks (ONNs) have emerged as high‐performance network accelerators, owing to its broad bandwidth and low power consumption. However, most current ONN architectures still struggle fully leverage their advantages in processing speed energy efficiency. Here, we demonstrate a large‐scale, ultra‐high‐speed, low‐power distributed parallel computing architecture, implemented on thin‐film lithium niobate platform. It can encode image information at modulation rate of 128...
Abstract Cell Adhesion Molecules (CAMs) play a crucial role in regulating immune responses and repairing damage caused by hypoxia. However, the relationship between expression characteristics of CAMs yak lung tissues their adaptation to plateau environment remains unclear. To address this question, we compared from yaks cattle at same altitude. After digesting with trypsin or Type I collagenase for varying durations, observed that fewer cells were isolated cattle. RNA sequencing (RNA-seq)...