Sylvie De Raedt
A5102898540- Acute Ischemic Stroke Management
- Stroke Rehabilitation and Recovery
- Intracerebral and Subarachnoid Hemorrhage Research
- Long-Term Effects of COVID-19
- Intensive Care Unit Cognitive Disorders
- COVID-19 and healthcare impacts
- Venous Thromboembolism Diagnosis and Management
- Cerebrovascular and Carotid Artery Diseases
- Heart Rate Variability and Autonomic Control
- Traumatic Brain Injury and Neurovascular Disturbances
- Neurosurgical Procedures and Complications
- Climate Change and Health Impacts
- Atrial Fibrillation Management and Outcomes
- Cardiac Imaging and Diagnostics
- Epilepsy research and treatment
- Medical Imaging Techniques and Applications
- Autoimmune Neurological Disorders and Treatments
- Intracranial Aneurysms: Treatment and Complications
- Migraine and Headache Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Anesthesia and Neurotoxicity Research
- Cerebral Palsy and Movement Disorders
- Healthcare Systems and Practices
- Otolaryngology and Infectious Diseases
- Trigeminal Neuralgia and Treatments
Universitair Ziekenhuis Brussel
2012-2025
Vrije Universiteit Brussel
2013-2025
Population Health Research Institute
2024
McMaster University
2024
Boston Medical Center
2021-2022
Boston University
2021-2022
Hospital de Egas Moniz
2022
University of Thessaly
2022
Hospital de Clínicas de Porto Alegre
2021
Grady Memorial Hospital
2021
<h3>Background and Objectives</h3> Declines in stroke admission, IV thrombolysis (IVT), mechanical thrombectomy volumes were reported during the first wave of COVID-19 pandemic. There is a paucity data on longer-term effect pandemic over course year through second We sought to measure admissions, intracranial hemorrhage (ICH), IVT, 1-year period at onset (March 1, 2020, February 28, 2021) compared with immediately preceding 2019, 29, 2020). <h3>Methods</h3> conducted longitudinal...
We assessed best available data on access and delivery of acute stroke unit (SU) care, intravenous thrombolysis (IVT) endovascular treatment (EVT) in the European region 2019 2020.We compared national per number inhabitants 100 annual incident first-ever ischaemic strokes (AIIS) 46 countries. Population estimates incidence were based United Nations Global Burden Disease Report 2019, respectively.The estimated mean SUs was 3.68 (95% CI: 2.90-4.45) one million (MIH) with 7/44 countries having...
Stroke Notetine clinical practice as a replacement of warfarin [2] .Data on the bleeding risk in patients treated with rtPA while taking dabigatran are nonexistent.We report 46-year-old right-handed woman presenting abrupt onset left hemiplegia and hemihypesthesia.NIHSS (The National Institutes Health Scale) score was 19.Conventional noncontrast computed tomography (CT) brain showed no abnormality.Perfusion CT revealed an extensive region decreased perfusion, mainly consisting ischemic...
Background and Purpose— Insulin-like growth factor I (IGF-I) is neuroprotective in animal models of stroke. We investigated whether serum IGF-I levels patients with acute ischemic stroke influence severity outcome. Methods— Concentrations IGF binding protein 3 were measured samples obtained within 6 hours after onset from 255 who took part the placebo arm United States Canadian Lubeluzole Acute Ischemic Stroke Study. was assessed National Institutes Health Scale. Multivariate analysis...
Abstract Background Delirium is an underdiagnosed and possibly preventable complication in acute stroke linked to poor outcome. Neutrophil-to-lymphocyte ratio (NLR), a marker of systemic inflammation, also associated with outcome after ischemic stroke. Aim To determine whether NLR predictor post-stroke delirium (PSD). Methods We reviewed the UZ Brussel database included 514 patients within 24 hours from onset between February 2009 December 2014. The presence was evaluated by two raters based...
Exploratory analysis of the phase 2 PACIFIC-Stroke (Program Anticoagulation via Inhibition FXIa by Oral Compound BAY 2433334-Non-Cardioembolic Stroke) randomized trial suggested that asundexian, an oral factor XIa inhibitor, prevents recurrent stroke and transient ischemic attacks in patients with atherosclerotic stroke. In this post hoc exploratory analysis, we hypothesized asundexian would be more effective enrolled large, multiple, or cortical acute infarcts on magnetic resonance imaging...
Background Recent data suggest that the true incidence of atrial fibrillation (AF) after patent foramen ovale (PFO) closure has probably been underestimated, and may differ according to type closing device used. Objectives On basis continuous rhythm monitoring with an implantable device, this study aims assess supraventricular arrhythmia following PFO Occlutech device. Methods This is a multicentric analysis consecutive patients treated between 01/01/2019 20/03/2024, loop recorder (IRL) (or...
Delirium is common in hospitalised patients, and there currently no specific treatment. Identifying treating underlying somatic causes of delirium the first priority once diagnosed. Several international guidelines provide clinicians with an evidence-based approach to screening, diagnosis symptomatic However, current do not offer a structured identification causes. A panel 37 internationally recognised experts from diverse medical backgrounds worked together modified Delphi via online...
Background and purpose: It is unclear whether pre‐stroke beta‐blockers use may influence stroke outcome. This study evaluates the independent effect of on ischaemic severity 3 months functional Methods: Pre‐stroke was investigated in 1375 patients who had been included two placebo‐controlled trials with lubeluzole. Stroke assessed by either National Institute Health Scale (NIHSS) or European (ESS). A modified Rankin scale (mRS) score >3 at used as measure for poor Results: Two hundred...
To investigate early changes in leukocyte subsets and autonomic function as predictors of the development poststroke infections.We assessed time course blood 59 patients with acute ischemic stroke. We divided into 2 groups: those who developed infections during first 7 days after stroke onset did not. measured urinary norepinephrine epinephrine concentrations pulse rate variability indices within 24 hours admission.We found that number circulating natural killer (NK) cells was higher (mean...
Quantification of stroke severity through telemedicine consultation is challenging and relies on professional support at the patient's bedside. We aimed to develop a novel scale for assessing without assistance from third party (Unassisted TeleStroke Scale [UTSS]).Stroke was assessed in 45 patients with suspicion acute by bedside examination using National Institutes Health Stroke (NIHSS) teleconsultation UTSS. reliability evaluated intrarater interrater variability, internal consistency,...
Background Spleen volume reduction followed by re-expansion has been described in acute ischemic stroke both animal and human studies. Splenic contraction might be partially due to sympathetic hyperactivity accompanied release of splenocytes the peripheral circulation, leading immunodepression. Aims To investigate whether spleen changes first week after are associated with post-stroke infections, lymphocytes count autonomic dysfunction. Methods In patients stroke, sizes were calculated from...
Long-term outcome and quality of life (QOL) in patients requiring prolonged mechanical ventilation after failure to wean the ICU is scarcely documented. We aimed evaluate long-term survival QOL discharged from with a tracheostomy for difficult weaning, or without ventilator dependency at discharge.We retrospectively investigated post-ICU trajectories weaning admitted medical tertiary center between 1999 2013, discriminating who were dependent weaned discharge. In 2014, assessment was done...
Background: A high Neutrophil-to-Lymphocyte ratio (NLR) in patients with acute ischemic stroke (AIS) has been associated post-stroke infections, but it's role as an early predictive biomarker for pneumonia (PSP) and urinary tract infection (UTI) is not clear. Aim: To investigate the usefulness of NLR obtained within 24 h after AIS predicting PSP UTI first week. Methods: Clinical laboratory data were retrieved from University Hospital Brussels database/electronic record system. Patients...