A5100361037- Acupuncture Treatment Research Studies
- Medical Research and Treatments
- Traditional Chinese Medicine Studies
- Traditional Chinese Medicine Analysis
- Healthcare and Venom Research
- Neurological Disease Mechanisms and Treatments
- Complementary and Alternative Medicine Studies
- Neurogenesis and neuroplasticity mechanisms
- Pharmacological Effects of Natural Compounds
- Cerebrospinal fluid and hydrocephalus
- Stroke Rehabilitation and Recovery
- Neuroinflammation and Neurodegeneration Mechanisms
- Plant-based Medicinal Research
- Alzheimer's disease research and treatments
- Gallbladder and Bile Duct Disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cardiovascular and exercise physiology
- Traumatic Brain Injury and Neurovascular Disturbances
- Metabolomics and Mass Spectrometry Studies
- Myofascial pain diagnosis and treatment
- Nerve injury and regeneration
- Advanced Neuroimaging Techniques and Applications
- Periodontal Regeneration and Treatments
- Chromatography in Natural Products
- Asthma and respiratory diseases
Tsinghua University
2025
Sun Yat-sen University
2024-2025
Sun Yat-sen University Cancer Center
2024-2025
Huazhong University of Science and Technology
2016-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
2016-2024
Beijing Tsinghua Chang Gung Hospital
2024
State Key Laboratory of Oncology in South China
2024
Tianjin University of Traditional Chinese Medicine
2011-2023
Stanford University
2023
Previous research has suggested that Xuebijing injection (XBJ), an herbal-based intravenous preparation, may reduce mortality among patients with sepsis.
Abstract The age-dependent decline in remyelination potential of the central nervous system during ageing is associated with a declined differentiation capacity oligodendrocyte progenitor cells (OPCs). molecular players that can enhance OPC or rejuvenate OPCs are unclear. Here we show that, mouse OPCs, nuclear entry SIRT2 impaired and NAD + levels reduced ageing. When supplement β-nicotinamide mononucleotide (β-NMN), an precursor, differentiation, were rescued aged animals. We effects on...
In the adult dentate gyrus (DG) and in proliferative zone lining lateral ventricle (LV-PZ), radial glia-like (RGL) cells are neural stem (NSCs) that generate granule neurons. A number of molecular markers including glial fibrillary acidic protein (GFAP), Sox2 nestin, can identify quiescent NSCs these two niches. However, to date, there is no marker distinguishes NSC origin DG versus LV-PZ. Hopx, an atypical homeodomain only protein, expressed by cell populations those intestine hair...
Objective: The "Glymphatic" system, a network of perivascular tunnels wrapped by astrocyte endfeet, was reported to be closely associated with the diseases central nervous system. Here, we investigated role glymphatic system in intracerebral hemorrhage (ICH) and its protective mechanism. Method: Experimental ICH model induced type IV collagenase rats. Cerebral lymphatic blockage ligation removal cervical lymph nodes. experimental rats were divided into sham-operated (SO) group, cerebral...
Objective— Vascular calcification is highly correlated with increased cardiovascular morbidity and mortality. C1q/tumor necrosis factor–related protein-3 (CTRP3) a newly identified adipokine that plays important roles in system. Here, we investigated the role of CTRP3 vascular its underlying mechanism. Approach Results— Adenine-induced chronic renal failure rat model was used to mimic process arterial medial calcification. The level elevated serum abdominal aorta rats. Periadventitial gene...
Aims: Vascular calcification is associated with cardiovascular death in patients chronic kidney disease (CKD). Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) plays an important role various diseases. However, its vascular remains unknown. Results: Adenine-induced rat CKD model was used to induce arterial medial calcification. The level of PGC-1α decreased abdominal aorta rats. Overexpression significantly ameliorated calcium deposition aorta, isolated carotid rings, and...
Acupuncture is an effective treatment for ischemic stroke (IS) and plays a key role in neurological rehabilitation after IS. can improve the clinical symptoms of various complications IS, including motor dysfunction, swallowing disorders, speech cognitive impairment, depression, insomnia, fatigue. However, mechanisms underlying effects acupuncture IS remain unclear. Available evidence suggests that may exert neuroprotective through neuroplasticity (neurogenesis synaptogenesis), angiogenesis,...
Background: The current American Joint Committee on Cancer (AJCC) T staging system was inaccurate in predicting the prognosis for perihilar cholangiocarcinoma (pCCA). This study aimed to propose a novel classification based depth of liver invasion (DOLI) pCCA.
Radiation-induced structural abnormalities in white matter (WM) have been reported patients with nasopharyngeal carcinoma (NPC); however, the alterations functional domain were insufficiently investigated. A total of 111 NPC included and these patients, based on whether completed radiation therapy (RT) or not, divided into pre-RT ( n = 47) post-RT 64) groups. Functional connectivity strength (FCS) between WM regions (WW-FCS) gray (GM) (GW-FCS) was used to investigate radiation-induced...
Adiponectin and adiponectin receptors (AdipoR1/2) are expressed in various tissues involved the regulation of multiple functions such as energy metabolism inflammatory responses. However, effect AdipoRs submandibular glands has not been fully evaluated. In present study, we found that mRNA protein both AdipoR1/2 were rat SMG-C6 cell line, evidenced by RT-PCR Western blot analysis. Immunofluorescence staining showed was diffused cytoplasm, while concentrated membrane acinar cells. Saliva flow...
Recently, digital signal processing (DSP) methods have been extensively studied and various DSP-based schemes proposed for next-generation passive optical network (PON). In this paper, we combine the time-division-multiplexing (TDM) architecture with advanced DSP to achieve high spectrum-efficiency colorless transmission. Orthogonal frequency division multiplexing (OFDM), as original form of frequency-domain equalization (FDE), is chosen both upstream downstream transmissions. TDM-PON based...
The Ras‑Raf‑mitogen‑activated protein kinase (MEK)1/2‑extracellular signal‑regulated (ERK)1/2 signaling pathway contributes to the release of chondral matrix‑degrading enzymes and accelerates degradation articular cartilage. Electroacupuncture (EA) treatment has been widely used for osteoarthritis (OA); however, mechanism underlying effects EA on OA remains unclear. Therefore, present study evaluated anti‑inflammatory potential mechanisms serum (EAS) tumor necrosis factor (TNF)‑α‑mediated...
XueBiJing, an injectable five-herb preparation, has been incorporated into routine sepsis care in China. Phthalides, originating from XueBiJing's component herbs <i>Ligusticum chuanxiong</i> rhizomes and <i>Angelica sinensis</i> roots, are believed to contribute its therapeutic effects due their presence the preparation antisepsis-related properties. This investigation aimed identify potential phthalides that bioavailable act on targets could serve as pharmacokinetic markers supplement...
To evaluate the clinical efficacy of a high-efficiency air purifier in patients with allergic rhinitis.We conducted randomised, double-blind, controlled trial active and inactive versions an purifier. Our study included rhinitis who were sensitive to Artemisia pollen treatment indoor environment using filtration at night. We evaluated during scattering season Yulin City Shanxi Province, China.The First Hospital (Yulin City, China).A total 90 allergens randomly assigned one two groups equal...
Background. Memory loss and cognitive impairment characterize the neurodegenerative disorder, Alzheimer’s disease (AD). Amyloid-β (Aβ) is key factor that triggers course of AD, reducing deposition Aβ in brain has been considered as a potential target for treatment AD. In clinical animal studies, electroacupuncture (EA) shown to be an effective recent years, substantial evidence accumulated suggesting important role glymphatic system clearance. Objective. The purpose this study was explore...