Anita Thapar
A5025343580- Attention Deficit Hyperactivity Disorder
- Child and Adolescent Psychosocial and Emotional Development
- Autism Spectrum Disorder Research
- Cognitive Abilities and Testing
- Health, Environment, Cognitive Aging
- Maternal Mental Health During Pregnancy and Postpartum
- Functional Brain Connectivity Studies
- Bipolar Disorder and Treatment
- Genetics and Neurodevelopmental Disorders
- Genetic Associations and Epidemiology
- Adolescent and Pediatric Healthcare
- Early Childhood Education and Development
- Birth, Development, and Health
- Congenital heart defects research
- Genomic variations and chromosomal abnormalities
- Children's Physical and Motor Development
- Family Support in Illness
- Infant Development and Preterm Care
- Neurotransmitter Receptor Influence on Behavior
- Epilepsy research and treatment
- Mental Health Research Topics
- Child and Adolescent Health
- Health disparities and outcomes
- Pharmacological Effects and Toxicity Studies
- Family Dynamics and Relationships
Cardiff University
2016-2025
Genomics (United Kingdom)
2010-2024
University College London
2012-2024
University of Connecticut
2024
University of Vermont
2024
University of Bristol
2010-2023
Wolfson Foundation
2023
Brighton and Sussex Medical School
2023
University of Cambridge
2021-2023
MRC Epidemiology Unit
2023
The neurodevelopmental hypothesis of schizophrenia provided a valuable framework that allowed condition usually presents with frank disorder in adolescence or early adulthood to be understood at least part as consequence events occurring development. However, the implications for nosological conceptions can only now fully appreciated. Recent research indicates genetic overlap between and syndromes which psychopathology is manifest childhood are often grouped together 'neurodevelopmental...
OBJECTIVE: The aim of this study was to examine whether smoking during pregnancy is associated with symptoms attention deficit hyperactivity disorder (ADHD) in offspring and these effects are additional genetic influences. METHOD: Children’s ADHD (parent- teacher-rated), maternal pregnancy, conduct symptoms, family adversity were assessed questionnaires for a population-based sample twins (1,452 twin pairs 5–16 years age). RESULTS: Although influences accounted most the variance ADHD, still...
Background Exposure to prenatal stress is associated with later adverse health and adjustment outcomes. This generally presumed arise through early environmentally mediated programming effects on the foetus. However, associations could factors that influence mothers' characteristics behaviour during pregnancy which are inherited by offspring. Method A ‘prenatal cross-fostering’ design where pregnant mothers related or unrelated their child as a result of in vitro fertilization (IVF) was used...
BackgroundIt is widely considered that exposure to maternal cigarette smoking in pregnancy has risk effects on offspring attention-deficit/hyperactivity disorder (ADHD). This view supported by consistent observations of association. It is, however, impossible be certain adequate control for confounding factors with observational designs. We use a novel "natural experiment" design separates prenatal environmental from alternative inherited effects.MethodsThe based conceived Assisted...
Objective: Attention deficit hyperactivity disorder (ADHD) is a common, highly heritable psychiatric disorder. Because of its multifactorial etiology, however, identifying the genes involved has been difficult. The authors followed up on recent findings suggesting that rare copy number variants (CNVs) may be important for ADHD etiology. Method: performed genome-wide analysis large, CNVs (<1% population frequency) in children with (N=896) and comparison subjects (N=2,455) from IMAGE II...
Background Families of children with attention deficit hyperactivity disorder (ADHD) report more negative family relationships than families without ADHD. Questions remain as to the role genetic factors underlying associations between and children's ADHD symptoms, symptoms an evocative influence on quality experienced within such families. Utilizing attributes two genetically sensitive research designs, present study examined biologically related nonbiologically maternal parenting practices,...
Abstract Attention-Deficit/Hyperactivity Disorder (ADHD) is a highly heritable childhood behavioral disorder affecting 5% of school-age children and 2.5% adults. Common genetic variants contribute substantially to ADHD susceptibility, but no individual have been robustly associated with ADHD. We report genome-wide association meta-analysis 20,183 cases 35,191 controls that identifies surpassing significance in 12 independent loci, revealing new important information on the underlying biology...
BackgroundAttention-deficit/hyperactivity disorder (ADHD) shows substantial heritability and is two to seven times more common in male individuals than female individuals. We examined putative genetic mechanisms underlying this sex bias: sex-specific heterogeneity higher burden of risk cases.MethodsWe analyzed genome-wide autosomal variants from the Psychiatric Genomics Consortium iPSYCH Project (n = 20,183 cases, n 35,191 controls) Swedish population register data 77,905 1,874,637...