A5025139592- Gut microbiota and health
- Probiotics and Fermented Foods
- Genomics and Phylogenetic Studies
- Clostridium difficile and Clostridium perfringens research
- Aquaculture disease management and microbiota
- Microbial Community Ecology and Physiology
- Pharmaceutical and Antibiotic Environmental Impacts
- Acute Myocardial Infarction Research
- Atherosclerosis and Cardiovascular Diseases
- Dental Health and Care Utilization
- Hydrology and Sediment Transport Processes
- Cardiac Fibrosis and Remodeling
- Molecular Biology Techniques and Applications
- Bacterial Identification and Susceptibility Testing
- Eosinophilic Disorders and Syndromes
- Protist diversity and phylogeny
- Biochemical and Structural Characterization
- Antimicrobial Peptides and Activities
- Polysaccharides and Plant Cell Walls
- Hydraulic flow and structures
- Iterative Methods for Nonlinear Equations
- Antimicrobial Resistance in Staphylococcus
- Chaos-based Image/Signal Encryption
- Vitamin C and Antioxidants Research
- Advanced Steganography and Watermarking Techniques
Guangdong Academy of Agricultural Sciences
2019-2025
Tianjin Chest Hospital
2017-2024
Zhejiang Lab
2023
Tianjin University
2022
Lanzhou University
2017
BGI Group (China)
2017
University of Chinese Academy of Sciences
2017
The gut microbiota has been linked to cardiovascular diseases. However, the composition and functional capacity of microbiome in relation diseases have not systematically examined. Here, we perform a metagenome-wide association study on stools from 218 individuals with atherosclerotic disease (ACVD) 187 healthy controls. ACVD deviates status by increased abundance Enterobacteriaceae Streptococcus spp. and, functionally, potential for metabolism or transport several molecules important...
To characterize the diversity and richness explore function structure of swine gut microbiome resistome in common pig-farming feedlots, we sampled metagenomic sequenced feces pigs from four different industrialized feedlots located distant provinces across China. Surprisingly, more than half nonredundant genes (1,937,648, 54.3%) current catalogue were newly found compared with previously published reference gene (RGC) pig microbiome. Additionally, 16 high-completeness draft genomes obtained...
The effects of a commercial probiotic (Clostridium butyricum) on growth, gut microbiota, digestion-related enzyme activity, antioxidant capacity and water quality in genetically improved, farmed tilapia (GIFT; Oreochromis niloticus) were assessed closed-circuit, container culture system. A basal diet containing commercially available C. butyricum at 3.0 × 1010, 1.5 1011 CFU/kg, control fed to fries for 90 days. Growth performances improved by treatment. Activities digestive enzymes (amylase,...
Antimicrobial peptides (AMPs) are a group of small peptides, which secreted by almost all creatures in nature. They have been explored therapeutic and agricultural aspects as they toxic to many bacteria. A considerable amount work has conducted analyzing 16S metagenomics the gastrointestinal (GI) microbiome grass carp (Ctenopharyngodon idellus). However, these datasets still untapped resources. In this present study, homologous search was performed predict AMPs from our newly generated...
Hyperlipidemia is a risk factor for various cardiovascular and metabolic disorders. And it tightly related to chronic inflammation. Interleukin-38 (IL-38) represents new member of anti-inflammatory cytokines. Thus we studied the important role IL-38 in hyperlipidemia development treatment.The mRNA level PBMCs (peripheral blood mononuclear cells) serum levels patients healthy controls were measured by real-time polymerase chain reaction (RT-PCR) enzyme-linked immunoassay (ELISA). The further...
Gut microbiomes in various fish species were widely investigated with the rapid development of next-generation sequencing technologies. However, little is known about gastrointestinal (GI) microbial communities mudskippers, a representative group marine amphibious fishes, and their comparisons other vertebrate animals from different habitats. Here, we performed comprehensive analysis on composition five groups (including freshwater aquatic amphibians, terrestrial animals) via operational...
The microbiota hosted in the pig gastrointestinal tract are important to health of this biomedical model. However, individual species and functional repertoires that make up gut microbiome remain largely undefined. Here we comprehensively investigated genomes functions piglet using culture-based metagenomics approaches. A collection included 266 cultured 482 metagenome-assembled (MAGs) were clustered 428 across 10 phyla was established. Among these species, 333 represent potential new...
Cardiovascular diseases seriously endanger human physical and mental health life safety, to investigate correlation between miR-let-7b miR-29b coronary artery calcification of various patients. At present, real-time fluorescence quantitative PCR (qRT-PCR) was used detect the expression levels plasma in patients with noncoronary analyze whether were different two groups. It shown that there no significant difference miR-let-7d-3p But observation group significantly lower than control group....
The aim of the present work was to investigate correlation plasma platelet-derived growth factor (PDGF)-BB level and single nucleotide polymorphism (SNP, rs1800817 rs2285094) PDGF-B gene with onset stability condition coronary heart disease (CHD).Totally, 335 subjects were included in divided into CHD (n = 247) control group 88) according angiography. Besides, patients acute syndrome (ACS) 165) stable angina pectoria (SAP) 82), based on condition. PDGF-BB measured by ELISA, genotype examined...
Percutaneous coronary intervention (PCI), as a relatively rapid and effective minimally invasive treatment for heart disease (CHD), can effectively relieve artery stenosis restore myocardial perfusion. However, the occurrence of major adverse cardiovascular events (MACE) is significant challenge post PCI care. To better understand risk/benefit indicators provide MACE prediction, 408 patients with CHD who had undergone from 2018 to 2021 in Tianjin Chest hospital were retrospectively studied...
In this paper, the solution of polynomial system arising from sparse interpolation problems with equally spaced sampling is studied. Exploiting special structure system, it proved that all its solutions lie in one orbit for generic data. Then, based on coefficient parameter homotopy method, an efficient algorithm solving proposed. Smoothness and accessibility hold constant terms start generated by a randomly chosen starting point. So, needs no computational cost first phase only path to be...
Abstract. Hydrological parameters should pass through a careful calibration procedure before aiding decision-making. However, great difficulties are encountered when applying methods to regions where runoff data inadequate. To fill the gap of hydrological for ungaged road network, we proposed Bayesian updating framework calibrate based on taxi GPS data. calibrated by adjusting their values such that generated acceptable parameter sets could yield disruption period during which no points...
Background: Staphylococcus aureus is a prominent pathogen responsible for human pyogenic and nosocomial infections. Although numerous studies on S. L-forms virulence are available in the literatures, there still various impediments research methods employed. Objectives: This study aimed to perform fluorescence reporter studying L-form its virulence, wild strain virulence. Methods: Newman-pCM29 which can express green fluorescent protein (GFP) was constructed used detect formation vitro vivo....
ABSTRACT Objective Hospital environment has been implicated in enrichment and exchange of pathogens antibiotic resistances, but its potential shaping the symbiotic microbial community hospital staff is unclear. This study was designed to evaluate alteration gut microbiome medical workers compared non-medical controls. Design Prospective cross-sectional cohort study. Setting Intensive care unit (ICU) other departments from a center northeast China. Subjects 175 healthy (1-3 months short-term...
Abstract -Purpose: The adaptability of blue-spotted mudskipper ( Boleophthalmus Periophthalmodon ; BP) and giant-fin Periophthalmus magnuspinnatus PM), has been previously reported at the genome level to explain their amphibious life. However, roles GI microbiota in adaptation terrestrial life are worth exploring. -Methods: In this study, we mainly utilized metagenomic data from these two representative mudskippers typical aquicolous fish species obtain microbial composition, diversity,...
Abstract Background: The microbiota hosted in the pig gastrointestinal tract are important to health of this biomedical model. However, individual species and functional repertoires that make up gut microbiome remain largely undefined. Results: Here we comprehensively investigated genomes functions piglet using culture-based metagenomics approaches. A collection included 266 cultured 482 metagenome-assembled (MAGs) were clustered 428 across 10 phyla was established. Among these species, 333...
ABSTRACT The microbiota hosted in the pig gastrointestinal tract are important for productivity of livestock. However, individual species and functional repertoires that make up gut microbiome remain largely undefined. Here we comprehensively investigated genomes functions piglet using culture-based metagenomics approaches. A collection included 266 cultured 482 metagenome-assembled (MAGs) were clustered to 428 across 10 phyla was established. Among these species, 333 represent potential new...