Julia M. Gauglitz
A5032648643- Metabolomics and Mass Spectrometry Studies
- Gut microbiota and health
- Advanced Chemical Sensor Technologies
- Bioinformatics and Genomic Networks
- Analytical Chemistry and Chromatography
- Isotope Analysis in Ecology
- Genomics and Phylogenetic Studies
- Computational Drug Discovery Methods
- Microbial Community Ecology and Physiology
- Mass Spectrometry Techniques and Applications
- Marine and coastal ecosystems
- Infant Nutrition and Health
- Liver Disease Diagnosis and Treatment
- Scientific Computing and Data Management
- Nutrition, Genetics, and Disease
- Mycobacterium research and diagnosis
- Bacterial Genetics and Biotechnology
- Advanced Proteomics Techniques and Applications
- Protist diversity and phylogeny
- Fatty Acid Research and Health
- Antimicrobial Peptides and Activities
- Breastfeeding Practices and Influences
- Indoor Air Quality and Microbial Exposure
- Diatoms and Algae Research
- Immune cells in cancer
University of Antwerp
2023-2024
University of California, San Diego
2018-2023
University of Montana
2018-2022
Universidad de Málaga
2021
Consejo Superior de Investigaciones Científicas
2021
Instituto de Hortofruticultura Subtropical y Mediterránea "La Mayora"
2021
Woods Hole Oceanographic Institution
2017-2020
La Jolla Alcohol Research
2020
University of California, Santa Barbara
2011-2016
University of California System
2014
We present QIIME 2, an open-source microbiome data science platform accessible to users spanning the research ecosystem, from scientists and engineers clinicians policy makers. 2 provides new features that will drive next generation of research. These include interactive spatial temporal analysis visualization tools, support for metabolomics shotgun metagenomics analysis, automated provenance tracking ensure reproducible, transparent science.
We present QIIME 2, an open-source microbiome data science platform accessible to users spanning the research ecosystem, from scientists and engineers clinicians policy makers. 2 provides new features that will drive next generation of research. These include interactive spatial temporal analysis visualization tools, support for metabolomics shotgun metagenomics analysis, automated provenance tracking ensure reproducible, transparent science.
Abstract Molecular networking connects mass spectra of molecules based on the similarity their fragmentation patterns. However, during ionization, commonly form multiple ion species with different behavior. As a result, these often remain unconnected in tandem spectrometry-based molecular networks, leading to redundant and disconnected sub-networks same compound classes. To overcome this bottleneck, we develop Ion Identity Networking (IIMN) that integrates chromatographic peak shape...
We present QIIME 2, an open-source microbiome data science platform accessible to users spanning the research ecosystem, from scientists and engineers clinicians policy makers. 2 provides new features that will drive next generation of research. These include interactive spatial temporal analysis visualization tools, support for metabolomics shotgun metagenomics analysis, automated provenance tracking ensure reproducible, transparent science.
Genomics and metabolomics are widely used to explore specialized metabolite diversity. The Paired Omics Data Platform is a community initiative systematically document links between metabolome (meta)genome data, aiding identification of natural product biosynthetic origins structures.
Abstract Despite the increasing availability of tandem mass spectrometry (MS/MS) community spectral libraries for untargeted metabolomics over past decade, majority acquired MS/MS spectra remain uninterpreted. To further aid in interpreting unannotated spectra, we created a nearest neighbor suspect library, consisting 87,916 annotated derived from hundreds millions originating published experiments. Entries this or “suspects,” were that could be linked molecular network to an spectrum....
Geochemical analyses of sedimentary barites (barium sulfates) in the geological record have yielded fundamental insights into chemistry Archean environment and evolutionary origin microbial metabolisms. However, question how were able to precipitate from a contemporary ocean that contained only trace amounts sulfate remains controversial. Here we report dissolved particulate multi-element barium-isotopic data Lake Superior evidence pelagic barite precipitation at micromolar ambient sulfate....
Abstract Molecular networking has become a key method used to visualize and annotate the chemical space in non-targeted mass spectrometry-based experiments. However, distinguishing isomeric compounds quantitative interpretation are currently limited. Therefore, we created Feature-based Networking (FBMN) as new analysis Global Natural Products Social (GNPS) infrastructure. FBMN leverages feature detection alignment tools enhance analyses isomer distinction, including from ion-mobility...
Standard workflows for analyzing microbiomes often include the creation and curation of phylogenetic trees. Here we present EMPress, an interactive web tool visualizing trees in context microbiome, metabolome, other community data scalable to with well over 500,000 nodes. EMPress provides novel functionality-including ordination integration animations-alongside many standard tree visualization features thus simplifies exploratory analyses forms 'omic data.IMPORTANCE Phylogenetic are integral...
Abstract Despite the increasing availability of tandem mass spectrometry (MS/MS) community spectral libraries for untargeted metabolomics over past decade, majority acquired MS/MS spectra remain uninterpreted. To further aid in interpreting unannotated spectra, we created a nearest neighbor suspect library, consisting 87,916 annotated derived from hundreds millions public spectra. Annotations were propagated based on structural relationships to reference molecules using MS/MS-based spectrum...
BackgroundObesity predominantly affects populations in high-income countries and those facing epidemiological transition. The risk of childhood obesity is increased among infants who had overweight or at birth, but low-resource settings one five are born small for gestational age. We aimed to study the relationships between: (1) maternal metabolite signatures; (2) fetal abdominal growth; (3) postnatal growth, adiposity, neurodevelopment.MethodsIn prospective, multinational, observational...
There is increasing epidemiological evidence supporting the association between onchocerciasis and seizures, reinforcing concept of onchocerciasis-associated epilepsy (OAE). The aim this paper to provide an update on new knowledge about OAE propose recommendations World Health Organization how address public health problem. During 2nd International Workshop held 19-21 September, 2023, in Antwerp, Belgium, participants recognised as a substantial yet neglected problem, particularly areas...
Characterization of dissolved organic matter in terms its composition and optical properties, with an eye toward ultimately understanding deep ocean dynamics, is the currently active frontier DOM research. We used UV-visible absorption spectroscopy fluorescence excitation-emission matrix (EEM) to characterize open along sections U.S. CO2/CLIVAR Repeat Hydrography Project located all major basins outside Arctic. Despite large differences intensity between basins, some variability patterns...
Crocosphaera is one of the major N 2 -fixing microorganisms in open ocean. On a global scale, process fixation important balancing budget, but factors governing rate remain poorly resolved. Here, we combine mechanistic model and both previous present laboratory studies to quantify how chemical such as C, N, Fe, O physical temperature light affect fixation. Our study shows that combines multiple mechanisms reduce intracellular protect -sensitive enzyme. model, however, indicates these...