A5101845638- Gut microbiota and health
- Animal Genetics and Reproduction
- Extracellular vesicles in disease
- Animal Nutrition and Physiology
- Genetic and phenotypic traits in livestock
- MicroRNA in disease regulation
- Diet and metabolism studies
- Probiotics and Fermented Foods
- Natural product bioactivities and synthesis
- Endoplasmic Reticulum Stress and Disease
- Ginger and Zingiberaceae research
- Biomarkers in Disease Mechanisms
- Phytochemical compounds biological activities
- Genomics, phytochemicals, and oxidative stress
- Plant Reproductive Biology
- Antibiotic Resistance in Bacteria
- Polymer-Based Agricultural Enhancements
- NF-κB Signaling Pathways
- Phytochemical Studies and Bioactivities
- Marine Sponges and Natural Products
- Genomics and Phylogenetic Studies
- IL-33, ST2, and ILC Pathways
- Competency Development and Evaluation
- Neuroinflammation and Neurodegeneration Mechanisms
- Dietary Effects on Health
Chongqing Academy of Animal Science
2017-2025
Guangzhou University of Chinese Medicine
2022-2024
Shanghai Library
2024
Xiangya Hospital Central South University
2023
Central South University
2023
Nanjing University of Chinese Medicine
2013-2021
Jiangsu Provincial Academy of Traditional Chinese Medicine
2017-2021
Nankai University
2020
Sichuan Agricultural University
2011-2017
Guangzhou Medical University
2016
Abstract The goose is an economically important waterfowl that exhibits unique characteristics and abilities, such as liver fat deposition fibre digestion. Here, we report de novo whole-genome assemblies for the swan describe evolutionary relationships among 7 bird species, including domestic wild geese, which diverged approximately 3.4~6.3 million years ago (Mya). In contrast to chickens a proximal expanded rapidly evolving genes found in genome are mainly involved metabolism, energy, amino...
To explore the impact of epigenetic modifications on egg-laying traits in geese, we employed genome-wide bisulfite sequencing (WGBS) to analyze DNA methylation patterns pituitary tissues high-(HYP) and low-yield (LYP) Sichuan White geese. We achieved high-quality data (mean 19.09 Gb raw reads, 15.49 clean 79.1% unique mapping rate) with a conversion efficiency 99.88%. Comparative analysis revealed 2394 differentially methylated regions (DMRs) 422 genes (DMGs) between HYP LYP groups....
Abstract High temperature and humidity in the environment are known to be associated with discomfort disease, yet underlying mechanisms remain unclear. We observed a decrease plasma glucagon-like peptide-1 levels response high-temperature conditions. Through 16S rRNA gene sequencing, alterations gut microbiota composition were identified following exposure high Notably, changes have been implicated bile acid synthesis. Further analysis revealed lithocholic Subsequent vitro experiments...
An overwhelming endoplasmic reticulum stress (ERS) and the following unfolded protein response (UPR) can induce hepatic inflammation, fibrosis hepatocellular carcinoma (HCC). Caudatin, one of species C‑21 steroidal glycosides mainly isolated from roots Cynanchum bungei Decne, exhibits potent anticancer activities in vivo. However, effect caudatin on HCC remains unclear. In present study, a diethylnitrosamine (DEN)‑induced model was established. Nodules tumors rat livers were monitored by...
To investigate the efficiency and optimum inclusion level of CA in growing geese diets on performance, plasma constituents, intestinal health, 240 healthy female at age 28d were randomly allotted six treatment incorporated with 0, 0.8, 1.6, 2.4, 3.2, 4% CA. Each group consisted five replicates eight birds per replicate. The findings demonstrated that 3.2% supplementation resulted improved growth performance (ADG, ADFI, FBW) (p = 0.001), who received also showed lower body fat contents <...
The genetic regulation of goose meat quality traits remains relatively unexplored, and the underlying mechanisms are yet to be elucidated. This study aims employ single nucleotide polymorphism (SNP) genotyping in conjunction with genome-wide association studies (GWAS) investigate critical candidate regions genes associated pH trait Sichuan white geese. A cohort 203 healthy male geese was randomly selected slaughtered at 70 days age. Measurements were taken pH, growth parameters, body...
Antibiotics are frequently used to treat bacterial infections; however, they affect not only the target pathogen but also commensal gut bacteria. They may cause dysbiosis of human intestinal microbiota and consequent metabolic alterations, as well spreading antibiotic resistant bacteria resistance genes (ARGs). In vitro experiments by simulator microbial ecosystem (SHIME) can clarify direct effects antibiotics on different regions microbiota, allowing complex be stably maintained in absence...
High-altitude pulmonary edema (HAPE) is a lifethreatening condition caused by acute exposure to high altitude.Accumulating evidence suggests that genetic factors play an important role in the etiology of HAPE.However, conclusions from association studies have been hindered limited sample size due rareness this disease.It known mitochondria are critical for hypoxic adaptation, and mitochondrial malfunction can be factor HAPE development.Therefore, we tested hypothesis ©FUNPEC-RP www.funpecrp.com.
With the worsening of greenhouse effect, correlation between damp-heat environment (DH) and incidence various diseases has gained increasing attention. Previous studies have demonstrated that DH can lead to intestinal disorders, enteritis, an up-regulation NOD-like receptor protein 3 (NLRP3). However, mechanism NLRP3 in this process remains unclear.
Aging increases the risks of various diseases and vulnerability to death. Cellular senescence is a hallmark aging that contributes greatly aging-related diseases. This study demonstrates extracellular vesicles from human urine-derived stem cells (USC-EVs) efficiently inhibit cellular
The objective of the study was to investigate mechanism by which dietary energy concentration regulates laying performance in geese. Eighty 558-day-old female Sichuan White geese were randomly allotted two treatments, each treatment fed 1 2 experimental diets containing 10.00 (deficient) or 11.80MJ/kg metabolizable (sufficient) for 30 days. Laying performance, hormone and gene expressions hypothalamus-pituitary-gonadal axis examined Birds sufficient-energy diet had significantly higher...
In the context of construction a skills-based society, this study statistically analyzes career conditions winners from 41st-46th WorldSkills Competitions across four provinces and cities in Yangtze River Delta. The main characteristics identified include relatively stable employment, preference for teaching positions as their first choice profession, focus on skill training work content, increasing flexibility employment opportunities over recent years. society has set new requirements...
Balanophora laxiflora Hemsl has been traditionally used to treat liver cancer. Eight ingredients were identified in the ethanol extracts of (BLE) by UHPLC-Q-TOF-MS/MS analysis. BLE inhibited viability and migration HepG2 Hepa1-6 cells, but triggered negligible apoptosis. also impeded glycolysis, glucose uptake lactate generation. Hexokinase II (HKII), a key enzyme involved was significantly repressed BLE. HKII plasmid enhanced cell migration, proliferation, which all abrogated pre-treatment....
Objective To investigate the relationship between miRNA-423-5p and left ventricular remodeling in patients with acute myocardial infarction, predictive values of for patients′ prognosis. Methods A total 248 STEMI who underwent primary percutaneous coronary intervention (PCI) from June 2012 to 2014 our department cardiology were enrolled followed up. Patients divided into three groups according plasma levels on admission: low-level group (miRNA-423-5p 0.72) including 82 cases.NT-proBNP...
To study the effects of Fe, Zn, B and Mn fertilizer with different ratio on yield quality Aconitum carmichaeli.Field experiment uniform design was applied, contents total alkaloids diester-alkaloids were measured.Fe, appropriate could promote growth vegetative organs, increase biomass, content Aconite significantly. Zn highly concentrated increased proportion first sub-roots, but inhibited other number roots less than that treatments, so it not conducive to formation production. High...