M. L. Purschke
- Particle physics theoretical and experimental studies
- High-Energy Particle Collisions Research
- Quantum Chromodynamics and Particle Interactions
- Particle Detector Development and Performance
- Radiation Detection and Scintillator Technologies
- Medical Imaging Techniques and Applications
- Distributed and Parallel Computing Systems
- Nuclear reactor physics and engineering
- Advanced Data Storage Technologies
- Advanced MRI Techniques and Applications
- Atomic and Subatomic Physics Research
- CCD and CMOS Imaging Sensors
- Nuclear Physics and Applications
- Analog and Mixed-Signal Circuit Design
- Radiomics and Machine Learning in Medical Imaging
- Dark Matter and Cosmic Phenomena
- Nuclear physics research studies
- Parallel Computing and Optimization Techniques
- Advanced X-ray and CT Imaging
- Plasma Diagnostics and Applications
- Particle Accelerators and Free-Electron Lasers
- Scientific Computing and Data Management
- Superconducting Materials and Applications
- Advanced Radiotherapy Techniques
- Research Data Management Practices
Brookhaven National Laboratory
2016-2025
University of Michigan–Ann Arbor
2025
Rensselaer Polytechnic Institute
2025
Oak Ridge National Laboratory
1994-2025
Central China Normal University
2025
Massachusetts Institute of Technology
2025
Los Alamos National Laboratory
2025
New Jersey Institute of Technology
2025
Georgia Institute of Technology
2025
Fermi National Accelerator Laboratory
2025
We developed a non-magnetic positron-emission tomography (PET) device based on the rat conscious animal PET that operates in small-animal magnetic resonance imaging (MRI) scanner, thereby enabling us to carry out simultaneous PET/MRI studies. The detector comprises 12 blocks, each being 4 × 8 array of lutetium oxyorthosilicate crystals (2.22 2.22 5 mm(3)) coupled matching avalanche photodiode array. housed plastic case, form 38 mm inner diameter ring with an 18 axial extent. Custom-built MRI...
Anesthesia is currently required for positron emission tomography (PET) studies of the animal brain in order to eliminate motion artifacts. However, anesthesia profoundly affects neurological state animal, complicating interpretation PET data. Furthermore, it precludes use study during normal behavior. The rat conscious tomograph (RatCAP) designed need studies. It a miniaturized full-ring scanner that attached directly head, imaging nearly entire brain. RatCAP utilizes arrays 2 mm /spl...
This R&D project, initiated by the DOE Nuclear Physics AI-Machine Learning initiative in 2022, leverages AI to address data processing challenges high-energy nuclear experiments (RHIC, LHC, and future EIC). Our focus is on developing a demonstrator for real-time of high-rate streams from sPHENIX experiment tracking detectors. The limitations 15 kHz maximum trigger rate imposed calorimeters can be negated intelligent use streaming technology system. approach efficiently identifies low...
Two-particle correlations of direct photons were measured in central 208Pb+208Pb collisions at 158A GeV. The invariant interferometric radii extracted for 100<K(T)<300 MeV/c and compared to from charged pion correlations. yield soft photons, K(T)<300 MeV/c, was the correlation strength theoretical calculations.
The Electron-Ion Collider (EIC), a state-of-the-art facility for studying the strong force, is expected to begin commissioning its first experiments in 2028. This an opportune time artificial intelligence (AI) be included from start at this and all phases that lead up experiments. second annual workshop organized by AI4EIC working group, which recently took place, centered on exploring current prospective application areas of AI EIC. not only beneficial EIC, but also provides valuable...
<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> The RatCAP has been designed and constructed to image the awake rat brain. In order maximize system performance, offline digital coincidence data processing algorithms including offset delay correction prompt delayed detection have developed validated. With using a singular value decomposition (SVD) technique, overall time resolution was improved from 32.6 17.6 ns FWHM. experimental results...
At Brookhaven National Laboratory, we are developing a simultaneous PET-MRI breast imaging system. A prototype II version of the PET system has been constructed. This device consists 24 detector blocks where each block 4 × 8 array 2.2 15 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> LYSO crystal directly coupled to non-magnetic APD array. The scanner an inner diameter 100 and axial extent 18 mm. Resolution measurements were carried...
Cerenkov technology is often the optimal choice for particle identification in high energy collision applications. Typically, most challenging regime at pseudorapidity (forward) where must perform well laboratory momenta. For upcoming Electron Ion Collider (EIC), physics goals require hadron ($\pi$, K, p) up to $\sim$~50 GeV/c. In this region Ring-Imaging viable solution.\newline The speed of light a radiator medium inversely proportional refractive index. Hence, PID reaching out momenta...
In the 2001-2002 running period of Relativistic Heavy Ion Collider (RHIC), transversely polarized protons were accelerated to 100 GeV for first time, with collisions at sqrt{s} = 200 GeV. We present results from this run single transverse spin asymmetries inclusive production neutral pions, photons and neutrons energy region 20 - forward backward angles between 0.3 mrad 2.2 respect proton direction. An asymmetry A_N (-0.090 +- 0.006 0.009) x (1.0^{+0.47}_{-0.24}) was observed neutron...
Neutral pion transverse momentum spectra were measured in p+C and p+Pb collisions at sqrt[S{NN}]=17.4 GeV midrapidity (2.3 less than or approximately equal eta{lab} 3.0) over the range 0.7 p{T} 3.5 GeV/c. The are compared to pi{0} Pb+Pb sqrt[S{NN}]=17.3 same experiment. For a wide of centralities (N{part} 300), yield pi{0}'s with greater 2 GeV/c is larger consistent yields scaled number nucleon-nucleon (N{coll}), while for central N{part}greater 350, suppressed.
Coincidence time resolution (CTR) in modern time-of-flight (TOF) PET scanners is limited by properties of the detector system, namely scintillator size and material, as well single-photon (SPTR) photon detection efficiency readout pixels. Recent studies have demonstrated effectiveness incorporating depth interaction (DOI) information into TOF to improve CTR. Having multiple timestamps per event has also been shown CTR through leading edge slope estimation. We propose using convolutional...
Front end digital signal processing and VME based DAQ electronics for the RatCAP (Rat Conscious Animal PET) is discussed. All approach to front mobile animal PET scanner presented. Altera Cyclone family FPGA realization of 12 channel TDC (time converter), address serial decoder system development discussed in detail. Routing delays between logic array blocks combined with propagation delay cells were used generate different clock phases, achieve subclock speed resolution. LogicLock/spl...
Abstract Pr 3+ ‐doped LuPO 4 emits UV radiation between 225 and 280 nm, where DNA shows strong absorption bands. Therefore, a systematic study of the luminescence doped is performed: Different doping concentrations, particles sizes, excitation schemes (vacuum at 160 nm X‐rays 50 kV, 2 mA, tungsten target) are compared. The emission spectra in range depends on energy particle size. Microcrystalline (6 µm) comprising 1% display highest intensity 234 upon vacuum as well X‐ray excitation....
RatCAP (Rat Conscious Animal PET) is miniature positron emission tomography scanner intended for neurological and behavioral study of small awake animal. The system comprises three distinct modules: rigid-flex technology based Printed Circuit Board (PCB) which houses the detector components front end Application Specific Integrated (ASIC), Time to Digital Converter Signal Processing module (TSPM) receives processes ASIC signals transmits processed data over two Giga bit fiber optic links PCI...
This work describes a fully 3D statistical image reconstruction for the RatCAP (Rat Conscious Animal PET) using Monte Carlo based system matrix. The consists of 12 Iutetium oxyorthosilicate (LSO)-avalanche photodiode (APD) detector blocks arranged in ring 41.2 mm diameter. Due to small diameter and low number total lines response (LORs), size complete matrix is comparison typical animal scanner. allows incorporation an accurate, RatCAP-specific physical model with inclusion crystal...
We propose to develop a high resolution scanner for simultaneous PET and MRI breast imaging that is capable of providing highly sensitive specific cancer examinations. The addition positron emission tomography capability an existing dedicated system will give device in which each the modalities contributes its strengths compensate weaknesses other. In this combined modality scanner, we have anatomical information from somewhat poorer PET, predictive power identifying type lesion overcome...