Katrina Tang
- Ovarian cancer diagnosis and treatment
- Endometriosis Research and Treatment
- Cancer-related molecular mechanisms research
- Endometrial and Cervical Cancer Treatments
- Cancer Genomics and Diagnostics
- Circular RNAs in diseases
- Cancer Mechanisms and Therapy
- Soft tissue tumor case studies
- Microtubule and mitosis dynamics
- Cancer-related Molecular Pathways
- RNA modifications and cancer
- Oral and Maxillofacial Pathology
- Genital Health and Disease
- Gestational Trophoblastic Disease Studies
- Radiomics and Machine Learning in Medical Imaging
- IgG4-Related and Inflammatory Diseases
- Pancreatic and Hepatic Oncology Research
- Neurofibromatosis and Schwannoma Cases
- Intraperitoneal and Appendiceal Malignancies
- Ethics in Clinical Research
- Polyomavirus and related diseases
- Colorectal Cancer Treatments and Studies
- Cancer and Skin Lesions
- Prenatal Screening and Diagnostics
- Angiogenesis and VEGF in Cancer
Prince of Wales Hospital
2018-2023
UNSW Sydney
2019-2023
The University of Melbourne
2023
Sydney Local Health District
2021
New South Wales Department of Health
2019
Liverpool Hospital
2013-2014
Abstract Background Cyclin E1 (CCNE1) is a potential predictive marker and therapeutic target in tubo‐ovarian high‐grade serous carcinoma (HGSC). Smaller studies have revealed unfavorable associations for CCNE1 amplification overexpression with survival, but to date no large‐scale, histotype‐specific validation has been performed. The hypothesis was that high‐level of overexpression, as well combination the two, are linked shorter overall survival HGSC. Methods Within Ovarian Tumor Tissue...
Abstract Gender-affirming hormone therapy (GAHT) is increasingly prescribed to transgender men and gender diverse individuals better align their affirmed identity somatic phenotype, aiming improve psychosocial well-being. However, the long-term outcomes of GAHT, especially risk hormone-related malignancy, remains unclear. We report a case man on GAHT with testosterone who developed recurrent hormone-sensitive endometrioid ovarian cancer. Treatment medroxyprogesterone acetate effectively...
Abstract ROR1 and ROR2 are receptor tyrosine kinases with altered expression in a range of cancers. Silencing or different tumour types has been shown to inhibit proliferation decrease metastatic potential. The aim this study was investigate the role endometrial cancer via immunohistochemistry (IHC) large patient cohort (n = 499) through vitro analysis cell lines. Correlation assessed between ROR1/2 clinicopathological parameters. Kaplan Meier curves were produced for 5-year progression free...
Abstract Purpose: Advanced-stage mucinous ovarian carcinoma (MOC) has poor chemotherapy response and prognosis lacks biomarkers to aid stage I adjuvant treatment. Differentiating primary MOC from gastrointestinal (GI) metastases the ovary is also challenging due phenotypic similarities. Clinicopathologic gene-expression data were analyzed identify prognostic diagnostic features. Experimental Design: Discovery analyses selected 19 genes with prognostic/diagnostic potential. Validation was...
Human biobanks are recognised as vital components of translational research infrastructure. With the growth in personalised and precision medicine, associated expansion biomarkers novel therapeutics under development, it is critical that researchers can access a strong collection patient biospecimens, annotated with clinical data. Biobanks globally undertaking transformation their operating models response to changing needs; transition from 'classic' model representing largely retrospective...
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<p>Supplementary Methods</p>
<p>Supplementary Methods</p>
<p>Supplementary Figures S1-S13</p>
<div>AbstractPurpose:<p>Advanced-stage mucinous ovarian carcinoma (MOC) has poor chemotherapy response and prognosis lacks biomarkers to aid stage I adjuvant treatment. Differentiating primary MOC from gastrointestinal (GI) metastases the ovary is also challenging due phenotypic similarities. Clinicopathologic gene-expression data were analyzed identify prognostic diagnostic features.</p>Experimental Design:<p>Discovery analyses selected 19 genes with...
<div>AbstractPurpose:<p>Advanced-stage mucinous ovarian carcinoma (MOC) has poor chemotherapy response and prognosis lacks biomarkers to aid stage I adjuvant treatment. Differentiating primary MOC from gastrointestinal (GI) metastases the ovary is also challenging due phenotypic similarities. Clinicopathologic gene-expression data were analyzed identify prognostic diagnostic features.</p>Experimental Design:<p>Discovery analyses selected 19 genes with...