A5016446658- Advanced Neuroimaging Techniques and Applications
- Functional Brain Connectivity Studies
- Neonatal and fetal brain pathology
- Cannabis and Cannabinoid Research
- Infant Development and Preterm Care
- Advanced MRI Techniques and Applications
- Schizophrenia research and treatment
- Traumatic Brain Injury Research
- Fetal and Pediatric Neurological Disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Neuroscience and Neuropharmacology Research
- Child and Adolescent Psychosocial and Emotional Development
- Autism Spectrum Disorder Research
- Cardiac Arrest and Resuscitation
- Stress Responses and Cortisol
- Hypothalamic control of reproductive hormones
- Neuroendocrine regulation and behavior
- Neural and Behavioral Psychology Studies
- Neural dynamics and brain function
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Genetics and Neurodevelopmental Disorders
- Cerebral Palsy and Movement Disorders
- Attention Deficit Hyperactivity Disorder
- Spinal Dysraphism and Malformations
- Mental Health and Psychiatry
Murdoch Children's Research Institute
2015-2024
The University of Melbourne
2015-2024
Royal Children's Hospital
2013-2024
Auckland University of Technology
2024
University of Auckland
2024
University of Stavanger
2024
Pediatrics and Genetics
2024
Washington University in St. Louis
2021
RMIT University
2021
Royal Women's Hospital
2021
<h3>Context</h3> Cannabis use can both increase and reduce anxiety in humans. The neurophysiological substrates of these effects are unknown. <h3>Objective</h3> To investigate the 2 main psychoactive constituents of<i>Cannabis sativa</i>(Δ9-tetrahydrocannabinol [Δ9-THC] cannabidiol [CBD]) on regional brain function during emotional processing. <h3>Design</h3> Subjects were studied 3 separate occasions using an event-related functional magnetic resonance imaging paradigm while viewing faces...
Cannabis use typically begins during adolescence and early adulthood, a period when cannabinoid receptors are still abundant in white matter pathways across the brain. However, few studies to date have explored impact of regular cannabis on structure, with no previous examining its axonal connectivity. The aim this study was examine fibre brain for evidence microstructural alterations associated long-term test whether age is severity any change. To end, diffusion-weighted magnetic resonance...
A common limitation of neuroimaging studies is their small sample sizes. To overcome this hurdle, the Enhancing Neuro Imaging Genetics through Meta-Analysis (ENIGMA) Consortium combines data from many institutions worldwide. However, introduces heterogeneity due to different scanning devices and sequences. ENIGMA projects commonly address with random-effects meta-analysis or mixed-effects mega-analysis. Here we tested whether batch adjustment method, ComBat, can further reduce site-related...
<h3>Context</h3> <i>Cannabis sativa</i>use can impair verbal learning, provoke acute psychosis, and increase the risk of schizophrenia. It is unclear where<i>C sativa</i>acts in human brain to modulate learning induce psychotic symptoms. <h3>Objectives</h3> To investigate effects 2 main psychoactive constituents of<i>C sativa</i>, Δ9-tetrahydrocannabinol (Δ9-THC) cannabidiol, on regional function during paired associate learning. <h3>Design</h3> Subjects were studied 3 separate occasions...
Cannabis sativa, the most widely used illicit drug, has profound effects on levels of anxiety in animals and humans. Although recent studies have helped provide a better understanding neurofunctional correlates these effects, indicating involvement amygdala cingulate cortex, their reciprocal influence is still mostly unknown. In this study dynamic causal modelling (DCM) Bayesian model selection (BMS) were to explore pure compounds C. sativa [600 mg cannabidiol (CBD) 10...
Measuring the distribution of brain tissue types (tissue classification) in neonates is necessary for studying typical and atypical development, such as that associated with preterm birth, may provide biomarkers neurodevelopmental outcomes. Compared magnetic resonance images adults, neonatal present specific challenges require development specialized, population-specific methods. This paper introduces MANTiS (Morphologically Adaptive Neonatal Tissue Segmentation), which extends unified...
Measures of physical growth, such as weight and height have long been the predominant outcomes for monitoring child health evaluating interventional in public studies, including those that may impact neurodevelopment. While growth generally reflects overall nutritional status, it lacks sensitivity specificity to brain developing cognitive skills abilities. Psychometric tools, e.g., Bayley Scales Infant Toddler Development, afford more direct assessment development but they require language...
Objectives: Even when euthymic bipolar disorder patients can have persistent deficits in working memory, but the neural basis of this deficit remains unclear. We undertook an functional magnetic resonance imaging investigation performing two memory paradigms; two‐back and Sternberg tasks, selected to examine central executive phonological loop respectively. hypothesized that neuronal dysfunction would be specific network underlying rather than component memory. Methods: Twelve right‐handed I...
The application of neurocognitive models to study schizophrenia has been influential in understanding the nature this complex and heterogeneous disorder. However, a comprehensive empirically validated account auditory hallucinations remains elusive. aim review was critically assess current evidence for specific deficits associated with verbal (AVHs) schizophrenia.A systematic literature search conducted research involving three cognitive hallucinations: those implicating dysfunction imagery,...
Niemann-Pick disease type C (NPC) is a progressive neurovisceral disorder with disrupted intracellular cholesterol metabolism that results in significant alterations to neuronal and axonal structure. Adult patients present ataxia, gaze palsy, impaired cognition, neuropsychiatric illness, but the neural substrate has not been well-characterized vivo. Our aim was investigate sample of adults confirmed NPC for gray white matter abnormalities.We utilized combination optimized voxel-based...