Sandra Rossi
A5056672063- Traumatic Brain Injury and Neurovascular Disturbances
- Traumatic Brain Injury Research
- Trauma and Emergency Care Studies
- Cardiac Arrest and Resuscitation
- Neurosurgical Procedures and Complications
- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Thermal Regulation in Medicine
- Cerebrospinal fluid and hydrocephalus
- COVID-19 Clinical Research Studies
- Italian Literature and Culture
- Acute Ischemic Stroke Management
- Airway Management and Intubation Techniques
- Hemodynamic Monitoring and Therapy
- Intracranial Aneurysms: Treatment and Complications
- S100 Proteins and Annexins
- Renaissance and Early Modern Studies
- Nosocomial Infections in ICU
- COVID-19 and Mental Health
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Hepatocellular Carcinoma Treatment and Prognosis
- Ultrasound in Clinical Applications
- Climate Change and Health Impacts
- Medieval Architecture and Archaeology
- COVID-19 and healthcare impacts
Helsinki University Hospital
2025
Ospedale di Parma
1998-2024
University of Parma
1985-2024
Azienda Unità Sanitaria Locale Della Romagna
2024
Opificio delle Pietre Dure
2023
University of Padua
2011-2022
University Hospital of North Norway
2021-2022
University of Groningen
2022
Azienda Ospedaliera di Padova
2011-2022
University Medical Center Groningen
2022
ARDS with COVID-19.An intermediate VT (7-8 ml/kg PBW) ventilation strategy was applied to the first four patients increase pulmonary efficiency eliminate CO 2 , and this used in next patients.Gas exchange consists of oxygenation ventilation.Oxygenation is quantified by Pa O /FI ratio, method has gained wide acceptance, particularly since publication Berlin definition (7).However, does not include additional pathophysiological information about ARDS, such as alveolar ventilation, measured...
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To assess the frequency of hyperthermia in a population acute neurosurgical patients; to relation between brain temperature (ICT) and core (Tc); investigate effect changes on intracranial pressure (ICP).The study involved 20 patients (10 severe head injury, eight subarachnoid haemorrhage, two neoplasms) with median Glasgow coma score (GCS) 6. ICP ICT were monitored by an intraventricular catheter coupled thermistor. Internal Tc was measured pulmonary artery Swan-Ganz catheter.Mean 38.4 (SD...
It is unclear whether in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, kidney injury (AKI) results from direct infection of the kidneys or complications arising course disease 2019 (COVID-19). Reports urinary abnormalities COVID-19 patients,S1 positive staining tubules viral antigens and complement components one autoptic series,1 visualization particles tubular epithelial cells podocytes on ultrastructural examination another,2 isolation SARS-CoV-2...
This study aimed at investigating the mechanisms underlying oxygenation response to proning and recruitment maneuvers in coronavirus disease 2019 (COVID-19) pneumonia.Twenty-five patients with COVID-19 pneumonia, variable times since admission (from 1 3 weeks), underwent computed tomography (CT) lung scans, gas-exchange lung-mechanics measurement supine prone positions 5 cmH2O during recruiting maneuver (supine, 35 cmH2O). Within non-aerated tissue, we differentiated atelectatic consolidated...
Abstract Chronic post-concussive symptoms are common after mild traumatic brain injury (mTBI) and difficult to predict or treat. Thalamic functional integrity is particularly vulnerable in mTBI may be related long-term outcomes but requires further investigation. We compared structural MRI resting state 108 patients with a Glasgow Coma Scale (GCS) of 13–15 normal CT, 76 controls. examined whether acute changes thalamic connectivity were early markers for persistent explored neurochemical...
Since 21 February 2020, Italy has developed an outbreak of coronavirus disease 2019 (COVID-19) by severe acute respiratory syndrome 2 (SARS-CoV-2), with 159 516 confirmed cases until 13 April, mostly concentrated in the Northern part country.1 This situation represents a massive stress for Italian healthcare system, forcing health authorities to take urgent measures limit spread and potentiate territorial Emergency systems intercept novel cases.2, 3 Public hospitals are subjected overflow...
A Covid-19 outbreak developed in Lombardy, Veneto and Emilia-Romagna (Italy) at the end of February 2020. Fear an imminent saturation available ICU beds generated notion that rationing intensive care resources could have been necessary.In order to evaluate impact on capacity manage critically ill patients, we performed a retrospective analysis first 2 weeks (February 24-March 8). Data were collected from regional registries case report form sent participating sites. increased 1545 1989...
Abstract Wooden panel paintings are among the most important historical and artistic artworks from Middle Ages Renaissance period. Currently, they represent a challenge for conservators scientists who face complex issues related to their conservation. Panel can be considered multilayer objects, that brevity consist of wooden support various paint layers. The is known hygroscopic continuously seeking equilibrium with humidity environment, thus it tends deform. Based on tests carried out 6...
Abstract Background After traumatic brain injury (TBI), fever is frequent. Brain temperature (BT), which directly linked to body temperature, may influence physiology. Increased and/or BT cause secondary damage, with deleterious effects on intracranial pressure (ICP), cerebral perfusion (CPP), and outcome. Methods Collaborative European NeuroTrauma Effectiveness Research in Traumatic Injury (CENTER-TBI), a prospective multicenter longitudinal study TBI Europe Israel, includes high resolution...
Ischemic complications account for significant patient morbidity following aneurysmal subarachnoid hemorrhage (aSAH). The Prevention and Treatment of Vasospasm with Clazosentan (REACT) study was designed to assess the safety efficacy clazosentan, an endothelin receptor antagonist, in preventing clinical deterioration due delayed cerebral ischemia (DCI) patients aSAH.
Excitatory Amino Acids (EAAs) release has been considered to be neurotoxic in traumatic brain injury patients. Microdialysis samples of extracellular space (ECS) and high glutamate concentrations cerebrospinal fluid (CSF) following Traumatic Brain Injury (TBI) have documented. The objective this study was determine the correlation between EAA ECS CSF focal diffuse injury. Head patients (GCS ≤ 8, n = 16) admitted Medical College Virginia Hospital were instrumented for microdialysis collection...
ObjectiveBedside chest ultrasonography, when integrated with clinical data, is an accurate tool for improving the diagnostic process of many respiratory diseases. This study aims to evaluate feasibility a ultrasonographic screening program in nursing homes detecting coronavirus disease-19 (COVID-19)–related pneumonia and appropriateness hospital referral residents.DesignPragmatic, descriptive, from April 2 9, 2020.Setting ParticipantsA total 83 older residents (age 85 ± 8) presenting mild...
Data regarding safety of bedside surgical tracheostomy in novel coronavirus 2019 (COVID-19) mechanically ventilated patients admitted to the intensive care unit (ICU) are lacking. We performed this study assess COVID-19 ICU. This retrospective, single-center, cohort observational (conducted between February, 23 and April, 30, 2020) was our 45-bed dedicated Inclusion criteria were: a) age over 18 years; b) confirmed diagnosis infection (with nasopharyngeal/oropharyngeal swab); c) invasive...
Importance The optimal timing for fixation of extremity fractures after traumatic brain injury (TBI) remains controversial. Objective To investigate whether patients who underwent within 24 hours TBI experienced worse outcomes than those had the procedure or more TBI. Design, Setting, and Participants This cohort study used data from Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study. Patients 16 years older with internal met inclusion...
BACKGROUND AND AIM OF THE WORK: The main purpose of the study is to investigate experience nurses who worked in Covid-19 area focusing on perception their role. In particular, has been explored nurses' job satisfaction relation images sent back by public opinion through mass media and social communication channels. During first wave have acquired visibility , but feeling represented more discomfort finding themselves suddenly glorified face a lack professional, social, economic recognition....
In our institution ICP was monitored in patients with GCS < or = 8 and abnormal CT scan: 362 severely head injured 180 subarachnoid hemorrhage. Mean duration of monitoring 103.6 hours (SD 74.96). Among 542 patients, 440 showed at least one episode above the threshold 20 mm Hg. only 71 (19.3%) had an lower than remaining 289 (81.7%) > Hg measured. 13 cases (2.2%) a ventricular infection has been diagnosed. 1 case intraparenchimal hemorrhage related to presence catheter detected. Elevated risk...
We evaluated the systemic and cerebral effects induced by an increase to 100% of inspired oxygen fraction (FiO2) on 20 comatose patients with head injury (9 patients) SAH (11 patients). Brain tissue tension (PtiO2) was measured through a Clark electrode inserted in penumbra-like areas. performed 55 hyperoxia tests increasing FiO2 from 35 ± 8% one second calculating PtiO2 index as: variation baseline at 1 minute/arterial (PaO2) minute x 100. One hundred percent caused both arterial (from 139...
Patients with adult respiratory distress syndrome (ARDS) and acute lung injury (ALI) have low concentrations of disaturated-phosphatidylcholine surfactant protein-B in bronchoalveolar lavage fluid. No information is available on their turnover.To analyze turnover patients ARDS/ALI human adults normal lungs (controls).2H2O as precursor disaturated-phosphatidylcholine-palmitate 113C-Leucine were administered intravenously to 12 8 controls. Disaturated-phosphatidylcholine isolated from serial...